RESTORING CARDIAC MECHANICAL FUNCTION BY POLYMERIC ARTIFICIAL MUSCULAR TISSUE

Informations projet

REPAIR

N° de convention de subvention: 952166

DOI 10.3030/952166

Date de signature de la CE 22 Juin 2020

Date de début 1 Septembre 2020

Date de fin 31 Août 2024

Financé au titre de

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Coût total € 3 909 707,50

Contribution de l’UE € 3 909 707,50

Coordonné par

UNIVERSITA DEGLI STUDI DI FIRENZE
Italy

Livrables

Websites, patent fillings, videos etc. (3)

Project Website
Preliminar Promotional material

Promotional material including updated results

Dissemination Kit for conferences and events

Dissemination Kit for conferences and events brochure summary explanantory videos

Open Research Data Pilot (2)

Data management plan.

Data management plan

Update of the data management plan

The data management plan will be updated

Publications

Peer reviewed articles (9)

Optical clearing in cardiac imaging: A comparative study

Auteurs: Olianti C, Giardini F, Lazzeri E, Costantini I, Silvestri L, Coppini R, Cerbai E, Pavone FS, Sacconi L.
Publié dans: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2022, ISSN 0079-6107
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.pbiomolbio.2021.07.012

Quantification of Myocyte Disarray in Human Cardiac Tissue

Auteurs: Giardini F, Lazzeri E, Vitale G, Ferrantini C, Costantini I, Pavone FS, Poggesi C, Bocchi L, Sacconi L.
Publié dans: Frontiers in Physiology, 2021, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2021.750364

Photoresponsive Polymer-Based Biomimetic ContractileUnits as Building Block for Artificial Muscles

Auteurs: Giulia Vitale, Bruno Grandinetti, Silvia Querceto, Daniele Martella, Chiara Tesi, Corrado Poggesi, Elisabetta Cerbai, Diederik S. Wiersma, Camilla Parmeggiani,* Cecilia Ferrantini,* and Leonardo Sacconi
Publié dans: Macromolecular Materials and Engineering, 2022, ISSN 1439-2054
Éditeur: Wiley
DOI: 10.1002/mame.202200187

Mesoscopic Optical Imaging of Whole Mouse Heart

Auteurs: Giardini F, Lazzeri E, Olianti C, Beconi G, Costantini I, Silvestri L, Cerbai E, Pavone FS, Sacconi L.
Publié dans: Journal of Visualized Experiments, 2021, ISSN 1940-087X
Éditeur: MYJoVE Corporation
DOI: 10.3791/62795

The Role of Crosslinker Molecular Structure on Mechanicaland Light-Actuation Properties in Liquid Crystalline Networks.

Auteurs: Simone Donato, Daniele Martella, Martina Salzano de Luna, Giulia Arecchi, Silvia Querceto, Cecilia Ferrantini, Leonardo Sacconi, Pierre-Louis Brient, Camille Chatard, Alain Graillot, Diederik S. Wiersma, Camilla Parmeggiani
Publié dans: Macromol. Rapid Commun., 2023, ISSN 1022-1336
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/marc.202200958

Coagulation Factor Xa Induces Proinflammatory Responses in Cardiac Fibroblasts via Activation of Protease-Activated Receptor-1

Auteurs: D’Alessandro, Elisa, Billy Scaf, Chantal Munts, Arne van Hunnik, Christopher J. Trevelyan, Sander Verheule, Henri M. H. Spronk, Neil A. Turner, Hugo ten Cate, Ulrich Schotten, and et al.
Publié dans: Cells, 2021, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells10112958

Cell instructive Liquid Crystalline Networks for myotube formation

Auteurs: Daniele Martella, Michele Mannelli, Roberta Squecco, Rachele Garella, Eglantina Idrizaj, Diego Antonioli, Michele Laus, Diederik S. Wiersma, Tania Gamberi, Paolo Paoli, Camilla Parmeggiani, Tania Fiaschi
Publié dans: iScience, 2021, ISSN 2589-0042
Éditeur: CellPress
DOI: 10.1016/j.isci.2021.103077

Slower Calcium Handling Balances Faster Cross-Bridge Cycling in Human MYBPC3 HCM

Auteurs: Josè Manuel Pioner, Giulia Vitale, Sonette Steczina, Marianna Langione, Francesca Margara, Lorenzo Santini, Francesco Giardini, Erica Lazzeri, Nicoletta Piroddi, Beatrice Scellini, Chiara Palandri, Maike Schuldt, Valentina Spinelli, Francesca Girolami, Francesco Mazzarotto, Jolanda van der Velden, Elisabetta Cerbai, Chiara Tesi, Iacopo Olivotto, Alfonso Bueno-Orovio, Leonardo Sacconi, Raffaele Co
Publié dans: Circulation Research, 2023, ISSN 0009-7330
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.122.321956

Genotype-Driven Pathogenesis of Atrial Fibrillation in Hypertrophic Cardiomyopathy: The Case of Different TNNT2 Mutations

Auteurs: Josè Manuel Pioner, Giulia Vitale, Francesca Gentile, Beatrice Scellini, Nicoletta Piroddi, Elisabetta Cerbai, Iacopo Olivotto, Jil Tardiff, Raffaele Coppini, Chiara Tesi, Corrado Poggesi and Cecilia Ferrantini*
Publié dans: frontiers in physiology, 2022, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2022.864547