Skip to main content

Fostering high scientific quality in protein research in Eastern Slovakia

Deliverables

Project quality plan

Definition of a quality strategy providing a cohesive focus on the critical phases of the project in a structured and integrated way definition of explicit evaluation criteria by which the work will be measured as it progresses and the quality assurance process

Kick- off meeting

Kick off meeting will be organized in the first month of the project and this deliverable will address the course and summary of this event

Report on protein stability and folding

Report on protein stability and folding will be a seminal document and a Project Milestone describing current progress in the understanding of protein folding and stability It will be reviewed by the Project Management Board in order to determine immediate directions in technical work and singlemolecule protein biophysics studies and to determine future changes in planned scientific work in this field

Report on direted evolution of proteins

The summarizing expert report on a reached stage of directed evolution methods ribosome and yeast displays at UPJS Besides the interim role as seed for the protein evolution methods expertise this report will be a crucial starting point for subsequent extremely competitive EU grant proposals submitted with the current Partners and additional participants

Plan of conference attendance in the first half of the project and its execution

The plan for the conference attendance in the first half of the project will be elaborated at the beginning of the project month 2 and will be thoroughly controlled throughout the first 18 months

Data management plan

We will participate in the Pilot on Open Research Data in Horizon 20201 According to this fact we will prepare a Data Management Plan DMP which will address the relevant aspects of making data FAIR findable accessible interoperable and reusable including what data the project will generate whether and how it will be made accessible for verification and reuse and how it will be curated and preserved

Construction of CasProt project website

The published web site will be available to the broadest public and a report on its contents and performance will be delivered to the Commission The project website will be the leading information resource concerning the Project and relevant activities The website will be regularly updated in order to reflect actual Project activities and publishable achievements

Questionnaire on the potential commercial impact of our research

This questionnaire will be sent to various potential business partners with the aim of revealing their interest in collaborating on commercialization of our products

Report on the Evolution of the publications in high impact journals in the relevant research fields

Introduction of the peer reviewed publications of the coordinating institution published during the three years preceding the start of the project into Continuous reporting tool on the Funding and tenders portal

Searching for OpenAIRE data...

Publications

Self-assembly of recombinant spider silk protein eADF4(C16) triggered by pH

Author(s): Talafová V., Žoldák G., Humenik M., Scheibel T., Sedlák E.
Published in: European Biophysics Journal: with Biophysics Letters, 2021, Page(s) 198, ISSN 0175-7571
Publisher: Springer-Nature

Development of haloalkane dehalogenases by ribosome display

Author(s): Dzurillová V., Berta M., Tomková M., Sedlák E.
Published in: European Biophysics Journal: with Biophysics Letters, 2021, Page(s) 122, ISSN 0175-7571
Publisher: Springer-Nature

The Brownian motion of flexible microstructures – towards viscosity measurements in microfluidic channels

Author(s): Slabý C., Kubacková J., Hovan A., Miškovský P., Tomori Z., Bánó G.
Published in: European Biophysics Journal: with Biophysics Letters, 2021, Page(s) 143, ISSN 0175-7571
Publisher: Springer-Nature

Role the conformational and colloidal stability on time-dependence solubility of human myeloma antibody λ-light chain

Author(s): Džupponová V., Žoldák G.
Published in: European Biophysics Journal: with Biophysics Letters, 2021, Page(s) 122, ISSN 0175-7571
Publisher: Springer-Nature

Self-assembly kinetic model of recombinant spider silk protein EADF4(C16)

Author(s): Talafová V., Humeník M., Žoldák G., Scheibel T., Sedlák E.
Published in: "26. Annual Congress of Czech and Slovak Societies for Biochemistry and Molecular Biology with cooperation of Austrian and German Biochemical Section: supported by the FEBS3+ Meeting programme: ""Life is Biochemistry, Biochemistry is Life"": programme and abstract book", 2021, Page(s) 188, ISBN 9788090777910
Publisher: Venice Praha, s.r.o.

SVK: Úloha disulfidových väzieb amyloidotického ľahkého reťazca IgG pri tvorbe extracelulárnych agregátov (ENG: The role of disulfide bonds of amyloidotic IgG light chain in the formation of extracellular aggregates)

Author(s): Ďzupponová V., Žoldák G.
Published in: Príroda len ťažko vydáva svoje tajomstvá: Zborník prác z vedeckej konferencie konanej pri príležitosti 100. výročia narodenia prof. MVDr. Michala Bartíka, DrSc., 2021, Page(s) 42-47, ISBN 9788080777241
Publisher: University of veterinary medicine and pharmacy in Košice

Salt-dependent antibody adsorption on water/solid interfaces

Author(s): Žoldák G., Džupponová, V.
Published in: Interfaces 2021: Book of abstracts, 2021, Page(s) 43
Publisher: Universita di Cagliari

Hofmeister effect on catalytic efficiency and conformation of 3C protease

Author(s): Dušeková E., Tomková M., Berta M., Dzurillová V., Sedláková D., Sedlák E.
Published in: European Biophysics Journal: with Biophysics Letters, 2021, Page(s) 121, ISSN 0175-7571
Publisher: Springer-Nature

Flavin cofactor in AsLOV2 domain as efficient singlet oxygen producer

Author(s): Petrenčáková M., Filandr F., Hovan A., Man P., Kožár T., Novák P., Jancura D., Bánó G., Sedlák E.
Published in: "26. Annual Congress of Czech and Slovak Societies for Biochemistry and Molecular Biology with cooperation of Austrian and German Biochemical Section: supported by the FEBS3+ Meeting programme: ""Life is Biochemistry, Biochemistry is Life"": programme and abstract book.", 2021, Page(s) 61, ISBN 9788090777910
Publisher: Venice Praha, s.r.o.

Preparation of a ribosome extract for an in vitro protein evolution through ribosome display

Author(s): Tomková M., Berta M., Dzurillová V., Sedlák E.
Published in: "26. Annual Congress of Czech and Slovak Societies for Biochemistry and Molecular Biology with cooperation of Austrian and German Biochemical Section: supported by the FEBS3+ Meeting programme: ""Life is Biochemistry, Biochemistry is Life"": programme and abstract book", 2021, Page(s) 181, ISBN 9788090777910
Publisher: Venice Praha, s.r.o.

SVK: Samozostavovanie rekombinantného pavúčieho proteínu do fibríl vplyvom pH a kozmotropných iónov (ENG: Self-assembly of recombinant spider silk protein eADF4(C16) triggered by pH and cosmotropic ions)

Author(s): Talafová V., Humenik M., Žoldák G., Scheibel T., Sedlák E.
Published in: Príroda len ťažko vydáva svoje tajomstvá: Zborník prác z vedeckej konferencie konanej pri príležitosti 100. výročia narodenia prof. MVDr. Michala Bartíka, DrSc., 2021, Page(s) 83-89, ISBN 9788080777241
Publisher: University of veterinary medicine and pharmacy in Košice

Thermodynamics of the formation and decay of the P-type ferryl formof cytochrome c oxidase in the reaction of the oxidized oxidase with H2O2

Author(s): Mikulova L., Pechova I., Stupak M., Fabian M., Jancura D.
Published in: European Biophysics Journal: with Biophysics Letters, 2021, Page(s) 126, ISSN 0175-7571
Publisher: Springer-Nature
DOI: 10.1007/s00249-021-01558-w

Modification of GPCR solubility by ribosome display

Author(s): Berta M., Dzurillová V., Tomková M., Sedlák E.
Published in: European Biophysics Journal: with Biophysics Letters, 2021, Page(s) 121, ISSN 0175-7571
Publisher: Springer-Nature

Autophagy and Apoptosis Induced in U87 MG Glioblastoma Cells by Hypericin-Mediated Photodynamic Therapy Can Be Photobiomodulated with 808 nm Light

Author(s): Pevna V., Wagnieres G., Huntosova V.
Published in: Biomedicines, 9, monthly, 2021, Page(s) 1703, ISSN 2227-9059
Publisher: mdpi
DOI: 10.3390/biomedicines9111703

Purification of MBP fusion proteins using engineered DARPinaffinity matrix

Author(s): Michal Nemergut, Rostislav Skrabana, Martin Berta, Andreas Plückthun, Erik Sedlak
Published in: International Journal of Biological Macromolecules: Structure, Function and Interactions, 187, 2021, Page(s) 105-112, ISSN 0141-8130
Publisher: Elsevier BV
DOI: 10.1016/j.ijbiomac.2021.07.117

SlyD Accelerates trans-to-cis Prolyl Isomerization in a Mechanosignaling Protein under Load

Author(s): Sengupta A., Rognoni L.E., Merkel U., Žoldák G., Rief M.
Published in: The Journal of Physical Chemistry B: Biophysical Chemistry, Biomaterials, Liquids, and Soft Matter, 125(31), 2021, Page(s) 8712–8721, ISSN 1520-5207
Publisher: American Chemical Society
DOI: 10.1021/acs.jpcb.1c03648

Interpretation of Single-Molecule Force Experiments on Proteins Using Normal Mode Analysis

Author(s): Bauer J., Žoldák G.
Published in: Nanomaterials, 11, 2021, Page(s) 2795, ISSN 2079-4991
Publisher: mdpi
DOI: 10.3390/nano11112795