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Ethically Responsible INnovations in reproductive medicine

Deliverables

Report on stakeholders' vision and needs towards ethically responsible innovations

The report on stakeholders vision and needs towards ethically responsible innovations engaging all stakeholder groups like geneticists gynaecologists genetic counsellors and specialists on ethical issues

Minutes of the Advisory Board workshops No 1

Minutes of the Advisory Board workshop No 1

Dissemination and communication plan

The dissemination and communication plan describing the activities to be carried out aiming to raise awareness about ERINs project among the target groups

Past Publications

Project peerreviewed publications in the particular field of research of the coordinatingentity during the three years preceding the start date of the project

Research collaboration strategy and action plan

The report describing the research collaboration strategy and action plan including the plans for project and grant proposals writing and steps to prepare highimpact research publications

Project Management and Quality Plan

The Project Management and Quality Plan describes the ERINs management structure and policies and delineates the quality management system needed for successfully fulfilling the projects aims

Data Management Plan

Data management plan for the project

Industry-academia network establishment

The report describing the development of industryacademia network

Publications

Hsa-mir-548 family expression in human reproductive tissues

Author(s): Ilmatar Rooda, Birgitta Kaselt, Maria Liivrand, Olli-Pekka Smolander, Andres Salumets, Agne Velthut-Meikas
Published in: BMC Genomic Data, 2021, ISSN 2730-6844
Publisher: Springer Nature
DOI: 10.1186/s12863-021-00997-w

From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns

Author(s): Lidiia Zhytnik, Maire Peters, Kadi Tilk, Kadri Simm, Neeme Tõnisson, Tiia Reimand, Katre Maasalu, Ganesh Acharya, Kaarel Krjutškov, Andres Salumets
Published in: Human Reproduction Update, 2021, ISSN 1460-2369
Publisher: Oxford University Press
DOI: 10.1093/humupd/dmab023

Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance

Author(s): Kreete Lüll, Merli Saare, Maire Peters, Ekaterina Kakhiani, Anastasia Zhdanova, Andres Salumets, Konstantin Boyarsky, Elin Org
Published in: Acta Obstetricia et Gynecologica Scandinavica, 2022, ISSN 1600-0412
Publisher: Wiley
DOI: 10.1111/aogs.14297

Liquid biopsy: state of reproductive medicine and beyond

Author(s): Gaby Schobers, Rebekka Koeck, Dominique Pellaers, Servi J C Stevens, Merryn V E Macville, Aimée D C Paulussen, Edith Coonen, Arthur van den Wijngaard, Christine de Die-Smulders, Guido de Wert, Han G Brunner, Masoud Zamani Esteki
Published in: Human Reprouction, 2021, ISSN 1460-2350
Publisher: Oxford University Press
DOI: 10.1093/humrep/deab206

Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report

Author(s): Lidiia Zhytnik, Maire Peters, Kadi Tilk, Tiia Reimand, Piret Ilisson, Tiina Kahre, Ülle Murumets, Aivar Ehrenberg, Eva-Liina Ustav, Neeme Tõnisson, Signe Mölder, Hindrek Teder, Kaarel Krjutškov & Andres Salumets
Published in: BMC Pregnancy and Childbirth, 2022, ISSN 1471-2393
Publisher: BioMed Central
DOI: 10.1186/s12884-022-04431-6

Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models

Author(s): Kristina Kiisholts; Kaido Kurrikoff; Piret Arukuusk; Ly Porosk; Maire Peters; Andres Salumets; Ülo Langel
Published in: Pharmaceutics, 2021, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13101618

Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples

Author(s): Priit Paluoja,Hindrek Teder,Amin Ardeshirdavani,Baran Bayindir,Joris Vermeesch,Andres Salumets,Kaarel Krjutškov,Priit Palta
Published in: PLOS Computational Biology, 2021, ISSN 1553-7358
Publisher: PLOS
DOI: 10.1371/journal.pcbi.1009684

Coupling miR/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity

Author(s): Nikolova M, Naydenov M, Glogovitis I, Apostolov A, Saare M, Boggavarapu N, Salumets A, Baev V, Yahubyan G.
Published in: Life, 2021, ISSN 2075-1729
Publisher: MDPI
DOI: 10.3390/life11121391

Decidualized endometrial stromal cells present with altered androgen response in PCOS

Author(s): Masuma Khatun, Alvin Meltsov, Darja Lavogina, Marina Loid, Keiu Kask, Riikka K. Arffman, Henna-Riikka Rossi, Freddy Lättekivi, Kersti Jääger, Kaarel Krjutškov, Ago Rinken, Andres Salumets, Terhi T. Piltonen
Published in: Scientific Reports, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-95705-0

Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study

Author(s): Läänelaid S, Ortega FB, Kunovac Kallak T, Joelsson L, Ruiz JR, Hreinsson J, Wånggren K, Stavreus-Evers A, Kalda R, Salumets A, Altmäe S.
Published in: International Journal of Environmental Research and Public Health, 2021, ISSN 1660-4601
Publisher: MDPI
DOI: 10.3390/ijerph18052718

Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization

Author(s): Darja Lavogina, Artjom Stepanjuk, Maire Peters, Külli Samuel, Sergo Kasvandik, Masuma Khatun, Riikka K Arffman, Erki Enkvist, Kaido Viht, Sergei Kopanchuk, Freddy Lättekivi, Agne Velthut-Meikas, Asko Uri, Terhi T Piltonen, Ago Rinken, Andres Salumets
Published in: Human Reproduction, 2021, ISSN 1460-2350
Publisher: Oxford University Press
DOI: 10.1093/humrep/deab161

Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis

Author(s): Simón-Gracia L, Kiisholts K, Petrikaitė V, Tobi A, Saare M, Lingasamy P, Peters M, Salumets A, Teesalu T.
Published in: Nanomaterials, 2021, ISSN 2079-4991
Publisher: MDPI
DOI: 10.3390/nano11123257

Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure

Author(s): Carolina von Grothusen, Caroline Frisendahl, Vijayachitra Modhukur, Parameswaran Grace Lalitkumar, Maire Peters, Omid R Faridani, Andres Salumets, Nageswara Rao Boggavarapu, Kristina Gemzell-Danielsson
Published in: Human Reproduction, 2022, ISSN 1460-2350
Publisher: Oxford University Press
DOI: 10.1093/humrep/deac019

Datasets

Additional file 1 of Hsa-mir-548 family expression in human reproductive tissues

Author(s): Rooda, Ilmatar; Kaselt, Birgitta; Liivrand, Maria; Smolander, Olli-Pekka; Salumets, Andres; Velthut-Meikas, Agne
Published in: figshare