Ethically Responsible INnovations in reproductive medicine

Resultado final

Report on stakeholders' vision and needs towards ethically responsible innovations

The report on stakeholders vision and needs towards ethically responsible innovations engaging all stakeholder groups like geneticists gynaecologists genetic counsellors and specialists on ethical issues

Minutes of the Advisory Board workshops No 1

Minutes of the Advisory Board workshop No 1

Dissemination and communication plan

The dissemination and communication plan describing the activities to be carried out aiming to raise awareness about ERINs project among the target groups

Past Publications

Project peerreviewed publications in the particular field of research of the coordinatingentity during the three years preceding the start date of the project

Research collaboration strategy and action plan

The report describing the research collaboration strategy and action plan including the plans for project and grant proposals writing and steps to prepare highimpact research publications

Project Management and Quality Plan

The Project Management and Quality Plan describes the ERINs management structure and policies and delineates the quality management system needed for successfully fulfilling the projects aims

Data Management Plan

Data management plan for the project

Industry-academia network establishment

The report describing the development of industryacademia network

Publicaciones

Hsa-mir-548 family expression in human reproductive tissues

Autores: Ilmatar Rooda, Birgitta Kaselt, Maria Liivrand, Olli-Pekka Smolander, Andres Salumets, Agne Velthut-Meikas
Publicado en: BMC Genomic Data, 2021, ISSN 2730-6844
Editor: Springer Nature
DOI: 10.1186/s12863-021-00997-w

From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns

Autores: Lidiia Zhytnik, Maire Peters, Kadi Tilk, Kadri Simm, Neeme Tõnisson, Tiia Reimand, Katre Maasalu, Ganesh Acharya, Kaarel Krjutškov, Andres Salumets
Publicado en: Human Reproduction Update, 2021, ISSN 1460-2369
Editor: Oxford University Press
DOI: 10.1093/humupd/dmab023

The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis

Autores: E Vargas; E García-Moreno; L Aghajanova; A Salumets; J A Horcajadas; F J Esteban; S Altmäe
Publicado en: Human Reproduction Open, Edición 23993529, 2022, ISSN 2399-3529
Editor: Oxford University Press
DOI: 10.1093/hropen/hoac016

In Reply: Revisiting Claims of the Continued Absence of Functional Germline Stem Cells in Adult Ovaries

Autores: Masahito Yoshihara; Magdalena Wagner; Anastasios Damdimopoulos; Cheng Zhao; Sophie Petropoulos; Shintaro Katayama; Juha Kere; Fredrik Lanner; Pauliina Damdimopoulou
Publicado en: Stem Cells, 2023, ISSN 1549-4918
Editor: Oxford University Press
DOI: 10.1093/stmcls/sxac084

Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse

Autores: Roos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A.
Publicado en: Frontiers in Endocrinology, Edición 16642392, 2022, ISSN 1664-2392
Editor: Frontiers Media S.A.
DOI: 10.3389/fendo.2022.945347

N-glycans from serum IgG and total serum glycoproteins specific for endometriosis

Autores: Kovács, Z., Reidy, F., Glover, L., McAuliffe, F. M., Stöckmann, H., Kilbane, M., Twomey, P. J., Peters, M., Saare, M., Rudd, P. M., Utt, M., Wingfield, M., Salumets, A., Saldova, R.
Publicado en: Scientific Reports, 2023, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-023-37421-5

Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay

Autores: Koel, M., Krjutškov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altmäe, S.
Publicado en: Human Reproduction Open, Edición 23993529, 2022, ISSN 2399-3529
Editor: Oxford University Press
DOI: 10.1093/hropen/hoac043

Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro

Autores: Lavogina, D., Visser, N., Samuel, K., Davey, E., Björvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P.
Publicado en: Frontiers in Endocrinology, Edición 16642392, 2022, ISSN 1664-2392
Editor: Frontiers Media S.A.
DOI: 10.3389/fendo.2022.903505

Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia

Autores: Bellavia, A., Zou, R., Björvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P.
Publicado en: Environmental Research, Edición 00139351, 2023, ISSN 0013-9351
Editor: Academic Press
DOI: 10.1016/j.envres.2022.114447

Transcriptomics and Spatial Proteomics for Discovery and Validation of Missing Proteins in the Human Ovary

Autores: Loren Méar; Xia Hao; Feria Hikmet; Pauliina Damdimopoulou; Kenny A. Rodriguez-Wallberg; Cecilia Lindskog
Publicado en: Journal of Proteome Research, 2023, ISSN 1535-3907
Editor: American Chemical Society
DOI: 10.1021/acs.jproteome.3c00545

Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial

Autores: Mändar, R., Sõerunurk, G., Štšepetova, J., Smidt, I., Rööp, T., Kõljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., Salumets, A.
Publicado en: Beneficial Microbes, 2023, ISSN 1876-2883
Editor: Wageningen Academic Publishers
DOI: 10.3920/bm2022.0091

Ambient black carbon particles in human ovarian tissue and follicular fluid

Autores: Eva Bongaerts, Katariina Mamia, Ilmatar Rooda, Richelle D. Björvang, Kiriaki Papaikonomou, Sebastian B. Gidlöf, Jan I. Olofsson, Marcel Ameloot, Ernesto Alfaro-Moreno, Tim S. Nawrot, Pauliina Damdimopoulou
Publicado en: Environment International, 2023, ISSN 1873-6750
Editor: Elsevier Ltd.
DOI: 10.1016/j.envint.2023.108141

Lactobacillus crispatus-dominated vaginal microbiome and Acinetobacter-dominated seminal microbiome support beneficial ART outcome

Autores: Kairi Koort, Kristiina Sõsa, Silver Türk, Eleri Lapp, Elle Talving, Peeter Karits, Karin Rosenstein, Madis Jaagura, Aire Sekavin, Deniss Sõritsa, Kai Haldre, Helle Karro, Paul Korrovits, Andres Salumets, Reet Mändar
Publicado en: Acta Obstetricia et Gynecologica Scandinavica, 2023, ISSN 1600-0412
Editor: John Wiley & Sons, Inc
DOI: 10.1111/aogs.14598

Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance

Autores: Kreete Lüll, Merli Saare, Maire Peters, Ekaterina Kakhiani, Anastasia Zhdanova, Andres Salumets, Konstantin Boyarsky, Elin Org
Publicado en: Acta Obstetricia et Gynecologica Scandinavica, 2022, ISSN 1600-0412
Editor: Wiley
DOI: 10.1111/aogs.14297

Liquid biopsy: state of reproductive medicine and beyond

Autores: Gaby Schobers, Rebekka Koeck, Dominique Pellaers, Servi J C Stevens, Merryn V E Macville, Aimée D C Paulussen, Edith Coonen, Arthur van den Wijngaard, Christine de Die-Smulders, Guido de Wert, Han G Brunner, Masoud Zamani Esteki
Publicado en: Human Reprouction, 2021, ISSN 1460-2350
Editor: Oxford University Press
DOI: 10.1093/humrep/deab206

AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles

Autores: Eleftheria Maria Panagiotou, Monica Kam Draskau, Tianyi Li, Angelica Hirschberg, Terje Svingen, Pauliina Damdimopoulou
Publicado en: Reproductive Toxicology, 2022, ISSN 0890-6238
Editor: Elsevier BV
DOI: 10.1016/j.reprotox.2022.07.004

The Dynamics of miR-449a/c Expression during Uterine Cycles Are Associated with Endometrial Development

Autores: Mladen Naydenov; Maria Nikolova; Apostol Apostolov; Ilias Glogovitis; Andres Salumets; Vesselin Baev; Galina Yahubyan
Publicado en: Biology, 2022, ISSN 2079-7737
Editor: MDPI
DOI: 10.3390/biology12010055

Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon

Autores: Lavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J.
Publicado en: Biosensors, 2022, ISSN 2079-6374
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios12040196

Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing

Autores: Wanwisa van Dijk; Kasper Derks; Marion Drüsedau; Jeroen Meekels; Rebekka Koeck; Rick Essers; Joseph Dreesen; Edith Coonen; Christine de Die-Smulders; Servi J C Stevens; Han G Brunner; Arthur van den Wijngaard; Aimée D C Paulussen; Masoud Zamani Esteki
Publicado en: Human Reproduction, 2022, ISSN 1460-2350
Editor: Oxford University Press
DOI: 10.1093/humrep/deac208

Users’ Concerns About Endometriosis on Social Media: Sentiment Analysis and Topic Modeling Study

Autores: Goel, R., Modhukur, V., Täär, K., Salumets, A., Sharma, R., Peters, M.
Publicado en: Journal of Medical Internet Research, 2023, ISSN 1438-8871
Editor: Journal of medical Internet Research
DOI: 10.2196/45381

Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report

Autores: Lidiia Zhytnik, Maire Peters, Kadi Tilk, Tiia Reimand, Piret Ilisson, Tiina Kahre, Ülle Murumets, Aivar Ehrenberg, Eva-Liina Ustav, Neeme Tõnisson, Signe Mölder, Hindrek Teder, Kaarel Krjutškov & Andres Salumets
Publicado en: BMC Pregnancy and Childbirth, 2022, ISSN 1471-2393
Editor: BioMed Central
DOI: 10.1186/s12884-022-04431-6

Induced pluripotent stem cells as a possible approach for exploring the pathophysiology of polycystic ovary syndrome (PCOS)

Autores: Khatun, M., Lundin, K., Naillat, F., Loog, L., Saarela, U., Tuuri, T., Salumets, A., Piltonen, T., Tapanainen, J. S.
Publicado en: Stem Cell Reviews and Reports, 2023, ISSN 2629-3277
Editor: Springer Nature
DOI: 10.1007/s12015-023-10627-w

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

Autores: Nilufer Rahmioglu, Sally Mortlock, Marzieh Ghiasi, Peter L. Møller, Lilja Stefansdottir, Geneviève Galarneau, Constance Turman, Rebecca Danning, Matthew H. Law, Yadav Sapkota, Paraskevi Christofidou, Sini Skarp, Ayush Giri, Karina Banasik, Michal Krassowski, Maarja Lepamets, Błażej Marciniak, Margit Nõukas, Danielle Perro, Eeva Sliz, Marta Sobalska-Kwapis, Gudmar Thorleifsson, Nura F. Topbas-
Publicado en: Nature Genetics, 2023, ISSN 1546-1718
Editor: Springer Nature Limited
DOI: 10.1038/s41588-023-01323-z

The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas

Autores: Saare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M.
Publicado en: Reproductive BioMedicine Online, Edición 14726483, 2022, ISSN 1472-6483
Editor: Reproductive Healthcare Ltd
DOI: 10.1016/j.rbmo.2022.05.028

Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models

Autores: Kristina Kiisholts; Kaido Kurrikoff; Piret Arukuusk; Ly Porosk; Maire Peters; Andres Salumets; Ülo Langel
Publicado en: Pharmaceutics, 2021, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13101618

At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale

Autores: Rebekka M Koeck; Florence Busato; Jorg Tost; Heleen Zandstra; Sylvie Remy; Sabine Langie; Marij Gielen; Ron van Golde; John C M Dumoulin; Han Brunner; Masoud Zamani Esteki; Aafke P A van Montfoort
Publicado en: Human Reproduction, 2022, ISSN 1460-2350
Editor: Oxford University Press
DOI: 10.1093/humrep/deac213

ExplORRNet: An interactive web tool to explore stage-wise miRNA expression profiles and their interactions with mRNA and lncRNA in human breast and gynecological cancers

Autores: Lawarde, A., Rahmani, E. S., Nath, A., Lavõgina, D., Jaal, J., Salumets, A., Modhukur, V.
Publicado en: Non-coding RNA Research, 2024, ISSN 2468-0540
Editor: Elsevier B.V.
DOI: 10.1016/j.ncrna.2023.10.006

Endometrial receptivity in women of advanced age: an underrated factor in infertility

Autores: Pathare, A. D. S., Loid, M., Saare, M., Gidlöf, S., Esteki, M. Z., Acharya, G., Peters, M., Salumets, A.
Publicado en: Human Reproduction Update, 2023, ISSN 1460-2369
Editor: Oxford University Press
DOI: 10.1093/humupd/dmad019

Spatial Proteomics for Further Exploration of Missing Proteins: A Case Study of the Ovary

Autores: Méar, L., Sutantiwanichkul, T., Östman, J., Damdimopoulou, P., Lindskog, C.
Publicado en: Journal of Proteome Research, 2022, ISSN 1535-3893
Editor: American Chemical Society
DOI: 10.1021/acs.jproteome.2c00392

Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples

Autores: Priit Paluoja,Hindrek Teder,Amin Ardeshirdavani,Baran Bayindir,Joris Vermeesch,Andres Salumets,Kaarel Krjutškov,Priit Palta
Publicado en: PLOS Computational Biology, 2021, ISSN 1553-7358
Editor: PLOS
DOI: 10.1371/journal.pcbi.1009684

Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities

Autores: Peters, Maire; Mikeltadze, Iveta; Karro, Helle; Saare, Merli; Estonian Biobank Research Team; Salumets, Andres; Mägi, Reedik; Laisk, Triin
Publicado en: Human Reproduction, Edición 2, 2022, ISSN 1460-2350
Editor: Oxford University Press
DOI: 10.1093/humrep/deac140

Prevalence of chromosomal alterations in first-trimester spontaneous pregnancy loss

Autores: Rick Essers, Igor N. Lebedev, Ants Kurg, Elizaveta A. Fonova, Servi J. C. Stevens, Rebekka M. Koeck, Ulrike von Rango, Lloyd Brandts, Spyridon Panagiotis Deligiannis, Tatyana V. Nikitina, Elena A. Sazhenova, Ekaterina N. Tolmacheva, Anna A. Kashevarova, Dmitry A. Fedotov, Viktoria V. Demeneva, Daria I. Zhigalina, Gleb V. Drozdov, Salwan Al-Nasiry, Merryn V. E. Macville, Arthur van den Wijngaard, J
Publicado en: Nature Medicine, 2023, ISSN 1078-8956
Editor: Nature Publishing Group
DOI: 10.1038/s41591-023-02645-5

Coupling miR/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity

Autores: Nikolova M, Naydenov M, Glogovitis I, Apostolov A, Saare M, Boggavarapu N, Salumets A, Baev V, Yahubyan G.
Publicado en: Life, 2021, ISSN 2075-1729
Editor: MDPI
DOI: 10.3390/life11121391

Autores: Marie-Therese Vinnars, Marie Bixo, Pauliina Damdimopoulou
Publicado en: Molecular and Cellular Endocrinology, 2023, ISSN 1872-8057
Editor: Elsevier B.V.
DOI: 10.1016/j.mce.2023.112064

Decidualized endometrial stromal cells present with altered androgen response in PCOS

Autores: Masuma Khatun, Alvin Meltsov, Darja Lavogina, Marina Loid, Keiu Kask, Riikka K. Arffman, Henna-Riikka Rossi, Freddy Lättekivi, Kersti Jääger, Kaarel Krjutškov, Ago Rinken, Andres Salumets, Terhi T. Piltonen
Publicado en: Scientific Reports, 2021, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-021-95705-0

Associations between lifestyle factors and levels of per- and polyfluoroalkyl substances (PFASs), phthalates and parabens in follicular fluid in women undergoing fertility treatment

Autores: Ida Hallberg; Richelle D. Björvang; Nermin Hadziosmanovic; Jacco Koekkoekk; Anne Pikki; Majorie van Duursen; Virissa Lenters; Ylva Sjunnesson; Jan Holte; Lars Berglund; Sara Persson; Matts Olovsson; Pauliina Damdimopoulou
Publicado en: Journal of Exposure Science & Environmental Epidemiology, 2023, ISSN 1559-064X
Editor: Springer Nature
DOI: 10.1038/s41370-023-00579-1

Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models

Autores: Li, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., Damdimopoulou, P.
Publicado en: Toxicology, 2023, ISSN 1879-3185
Editor: Elsevier
DOI: 10.1016/j.tox.2023.153425

Reference standards for follicle density in ovarian cortex from birth to sexual maturity

Autores: Hassan, J., Knuus, K., Lahtinen, A., Rooda, I., Otala, M., Tuuri, T., Gidlöf, S., Edlund, E., Menezes, J., Malmros, J., Byström, P., Sundin, M., Langenskiöld, C., Vogt, H., Frisk, P., Petersen, C., Damdimopoulou, P., Jahnukainen, K.
Publicado en: Reproductive Biomedicine Online, 2023, ISSN 1472-6483
Editor: Reproductive Healthcare Ltd
DOI: 10.1016/j.rbmo.2023.103287

The Continued Absence of Functional Germline Stem Cells in Adult Ovaries

Autores: Yoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., Damdimopoulou, P.
Publicado en: Stem Cells, 2022, ISSN 1549-4918
Editor: Oxford University Press
DOI: 10.1093/stmcls/sxac070

Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study

Autores: Läänelaid S, Ortega FB, Kunovac Kallak T, Joelsson L, Ruiz JR, Hreinsson J, Wånggren K, Stavreus-Evers A, Kalda R, Salumets A, Altmäe S.
Publicado en: International Journal of Environmental Research and Public Health, 2021, ISSN 1660-4601
Editor: MDPI
DOI: 10.3390/ijerph18052718

Genome-wide association study in Estonia reveals importance of vaginal epithelium associated genes in case of recurrent vaginitis

Autores: Mutli, E., Mändar, R., Koort, K., Salumets, A., Team, E. B. R., Laisk, T.
Publicado en: Journal of Reproductive Immunology, 2024, ISSN 0165-0378
Editor: Elsevier BV
DOI: 10.1016/j.jri.2024.104216

Dynamic changes in AI-based analysis of endometrial cellular composition: Analysis of PCOS and RIF endometrium

Autores: Lee, S., Arffman, R. K., Komsi, E. K., Lindgren, O., Kemppainen, J., Kask, K., Saare, M., Salumets, A., Piltonen, T.
Publicado en: Journal of Pathology Informatics, 2024, ISSN 2153-3539
Editor: Elsevier Inc.
DOI: 10.1016/j.jpi.2024.100364

Identification of phthalate mixture exposure targets in the human and mouse ovary in vitro

Autores: Tarvainen, I., Soto, D. A., Laws, M. J., Björvang, R. D., Damdimopoulos, A., Roos, K., Li, T., Kramer, S., Li, Z., Lavogina, D., Visser, N., Kallak, T. K., Lager, S., Gidlöf, S., Edlund, E., Papaikonomou, K., Öberg, M., Olovsson, M., Salumets, A., Velthut-Meikas, A., Flaws, J.A., Damdimopoulou, P.
Publicado en: Reproductive Toxicology, 2023, ISSN 0890-6238
Editor: Elsevier BV
DOI: 10.1016/j.reprotox.2023.108393

Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles

Autores: Modhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A.
Publicado en: Cancers, 2021, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13153768

Unveiling the etiology of peritonsillar abscess using next generation sequencing

Autores: Minha, S., Vaikjärv, R., Parm, Ü., Kasenõmm, P., Kõljalg, S., Sepp, E., Jaagura, M., Salumets, A., Štšepetova, J., Mändar, R.
Publicado en: Annals of Clinical Microbiology and Antimicrobials, 2023, ISSN 1476-0711
Editor: BioMed Central
DOI: 10.1186/s12941-023-00649-0

The Upper Reproductive System Microbiome: Evidence beyond the Uterus

Autores: Analuce Canha-Gouveia, Valentina Di Nisio, Andres Salumets, Pauliina Damdimopoulou, Pilar Coy, Signe Altmäe, Alberto Sola-Leyva
Publicado en: Seminars in Reproductive Medicine, 2023, ISSN 1526-8004
Editor: Thieme Medical Publishers
DOI: 10.1055/s-0043-1778056

Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis

Autores: Piotr Laudański, Gabriela Rogalska, Damian Warzecha, Michał Lipa, Grzegorz Mańka, Mariusz Kiecka, Robert Spaczyński, Piotr Piekarski, Beata Banaszewska, Artur Jakimiuk, Tadeusz Issat, Wojciech Rokita, Jakub Młodawski, Maria Szubert, Piotr Sieroszewski, Grzegorz Raba, Kamil Szczupak, Tomasz Kluz, Marek Kluza, Toomas Neuman, Priit Adler, Hedi Peterson, Andres Salumets, Miroslaw Wielgos
Publicado en: Human Reproduction, 2023, ISSN 1460-2350
Editor: Oxford University Press
DOI: 10.1093/humrep/dead011

Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization

Autores: Darja Lavogina, Artjom Stepanjuk, Maire Peters, Külli Samuel, Sergo Kasvandik, Masuma Khatun, Riikka K Arffman, Erki Enkvist, Kaido Viht, Sergei Kopanchuk, Freddy Lättekivi, Agne Velthut-Meikas, Asko Uri, Terhi T Piltonen, Ago Rinken, Andres Salumets
Publicado en: Human Reproduction, 2021, ISSN 1460-2350
Editor: Oxford University Press
DOI: 10.1093/humrep/deab161

Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences

Autores: Rebekka M. Koeck; Florence Busato; Jorg Tost; Dimitri Consten; Jannie van Echten-Arends; Sebastiaan Mastenbroek; Yvonne Wurth; Sylvie Remy; Sabine Langie; Tim S. Nawrot; Michelle Plusquin; Rossella Alfano; Esmée M. Bijnens; Marij Gielen; Ron van Golde; John C. M. Dumoulin; Han Brunner; Aafke P. A. van Montfoort; Masoud Zamani Esteki
Publicado en: npj Genomic Medicine, Edición 1, 2022, ISSN 2056-7944
Editor: Springer Nature
DOI: 10.1038/s41525-022-00310-3

Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes

Autores: Anh Thi Chau Nguyen, Na Thi Le Nguyen, Thu Thi Anh Hoang, Tuyen Thi Nguyen, Trang Thi Quynh Tran, Dan Nu Tam Tran, Anh Thi Kim Nguyen, Linh Manh Tran, Duc Huu Chau Nguyen, Tam Minh Le, Binh Duy Ho, Tiiu Rööp, Siiri Kõljalg, Jelena Štšepetova, An Van Le, Andres Salumets & Reet Mändar
Publicado en: BMC Pregnancy and Childbirth, 2022, ISSN 1471-2393
Editor: BioMed Central

Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis

Autores: Simón-Gracia L, Kiisholts K, Petrikaitė V, Tobi A, Saare M, Lingasamy P, Peters M, Salumets A, Teesalu T.
Publicado en: Nanomaterials, 2021, ISSN 2079-4991
Editor: MDPI
DOI: 10.3390/nano11123257

Investigating the impact of vitrification on bovine ovarian tissue morphology, follicle survival, and transcriptomic signature

Autores: Deligiannis, S. P., Kask, K., Modhukur, V., Boskovic, N., Ivask, M., Jaakma, Ü., Damdimopoulou, P., Tuuri, T., Velthut-Meikas, A., Salumets, A.
Publicado en: Journal of Assisted Reproduction and Genetics, 2024, ISSN 1058-0468
Editor: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s10815-024-03038-4

Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure

Autores: Carolina von Grothusen, Caroline Frisendahl, Vijayachitra Modhukur, Parameswaran Grace Lalitkumar, Maire Peters, Omid R Faridani, Andres Salumets, Nageswara Rao Boggavarapu, Kristina Gemzell-Danielsson
Publicado en: Human Reproduction, 2022, ISSN 1460-2350
Editor: Oxford University Press
DOI: 10.1093/humrep/deac019

Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders

Autores: P. Auvinen; J. Vehviläinen; H. Marjonen; V. Modhukur; J. Sokka; E. Wallén; K. Rämö; L. Ahola; A. Salumets; T. Otonkoski; H. Skottman; M. Ollikainen; R. Trokovic; H. Kahila; N. Kaminen-Ahola
Publicado en: BMC Medicine, 2022, ISSN 1741-7015
Editor: BioMed Central
DOI: 10.1186/s12916-022-02699-1

An integrative analysis of endometrial steroid metabolism and transcriptome in relation to endometrial receptivity in in vitro fertilization patients

Autores: Brentjens, L. S., Obukhova, D., Hartog, J. D., Delvoux, B., Koskivuori, J., Auriola, S., Häkkinen, Bui, B., Van Hoogenhuijze, N., Mackens, S., Mol, F., De Bruin, J., Besselink, D., Teklenburg, G., Kukushkina, V., Salumets, A., Broekmans, F., Van Golde, R., Esteki, M. Z., Romano, A.
Publicado en: F&S Science, 2023, ISSN 2666-335X
Editor: Elsevier
DOI: 10.1016/j.xfss.2023.04.003

Targeted gene expression profiling for accurate endometrial receptivity testing

Autores: Alvin Meltsov, Merli Saare, Hindrek Teder, Priit Paluoja, Riikka K. Arffman, Terhi Piltonen, Piotr Laudanski, Mirosław Wielgoś, Luca Gianaroli, Mariann Koel, Maire Peters, Andres Salumets, Kaarel Krjutškov, Priit Palta
Publicado en: Scientific Reports, 2023, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-023-40991-z

The cervical transcriptome changes during the menstrual cycle but does not predict the window of implantation

Autores: Pathare, A. D. S., Saare, M., Meltsov, A., Lawarde, A., Modhukur, V., Kalinina, A., Sekavin, A., Kukushkina, V., Karro, H., Salumets, A., Peters, M.
Publicado en: Frontiers in Reproductive Health, 2023
Editor: Frontiers Media
DOI: 10.3389/frph.2023.1224919

Artificial intelligence in scientific writing: a friend or a foe?

Autores: Signe Altmäe, Alberto Sola-Leyva, Andres Salumets
Publicado en: Reproductive BioMedicine Online, 2023, ISSN 1472-6491
Editor: Elsevier
DOI: 10.1016/j.rbmo.2023.04.009

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