Training experts in antigen processing to deliver new drug prototypes for cancer and autoimmune diseases

Project description

Insight into antigen processing in autoimmunity and cancer

Accumulating evidence indicates that ERAP enzymes cleave proteins to generate antigenic peptides for presentation to the immune system. As a result, these enzymes constitute attractive targets for modulating the immune system to fight autoimmune disorders and cancer. The EU-funded CAPSTONE project aims to investigate the mechanisms underlying the antigen processing dysfunction encountered in these diseases and the implication of ERAP enzymes. With a long-term goal to develop innovative therapeutic drugs, CAPSTONE will bring together an intersectoral and multidisciplinary group of experts. More importantly, it will train early-stage researchers and prepare them for a career in academia or the pharmaceutical industry.

Fields of science

• medical and health sciences › basic medicine › immunology › autoimmune diseases
• medical and health sciences › health sciences › public and environmental health › epidemics prevention › immunisation
• medical and health sciences › basic medicine › medicinal chemistry
• natural sciences › chemical sciences › analytical chemistry › mass spectrometry
• medical and health sciences › basic medicine › immunology › immunotherapy
• medical and health sciences › clinical medicine › cancer

Programme(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
• H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers

Topic(s)

• MSCA-ITN-2020 - Innovative Training Networks

Call for proposal

H2020-MSCA-ITN-2020
See other projects for this call

Funding Scheme

MSCA-ITN-ETN - European Training Networks

Coordinator

UNIVERSITE DE LILLE

Address

42 Rue Paul Duez
59800 Lille
France

Activity type

Higher or Secondary Education Establishments

EU contribution

€ 549 604,08

Participants (9)

"NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS"""

Greece

EU contribution

€ 486 035,28

Address

End Of Patriarchou Grigoriou E And 27 Neapoleos Street
15341 Agia Paraskevi

Activity type

Research Organisations

UNIVERSITY OF SOUTHAMPTON

United Kingdom

EU contribution

€ 606 345,12

Address

Highfield
SO17 1BJ Southampton

Activity type

Higher or Secondary Education Establishments

UNIVERSITE DE PARIS

France

EU contribution

€ 549 604,08

Address

85 Bd Saint Germain
75006 Paris

Activity type

Higher or Secondary Education Establishments

OSPEDALE PEDIATRICO BAMBINO GESU

Italy

EU contribution

€ 522 999,36

Address

Piazza Sant Onofrio 4
00165 Roma

Activity type

Research Organisations

ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON

Greece

EU contribution

€ 243 017,64

Address

6 Christou Lada Str
10561 Athina

Activity type

Higher or Secondary Education Establishments

UNIVERSITAIR MEDISCH CENTRUM UTRECHT

Netherlands

EU contribution

€ 265 619,88

Address

Heidelberglaan 100
3584 CX Utrecht

Activity type

Higher or Secondary Education Establishments

IMABIOTECH SAS

France

EU contribution

€ 274 802,04

Address

152 Rue Du Docteur Yersin
59120 Loos

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

INOCURE SRO

Czechia

EU contribution

€ 234 871,56

Address

Politickych Veznu 935/13
11000 Praha

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

NOVAMECHANICS LIMITED

Cyprus

EU contribution

€ 235 836,72

Address

Digeni Akrita 51
1070 Nicosia

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)