Skip to main content

Training experts in antigen processing to deliver new drug prototypes for cancer and autoimmune diseases

Project description

Insight into antigen processing in autoimmunity and cancer

Accumulating evidence indicates that ERAP enzymes cleave proteins to generate antigenic peptides for presentation to the immune system. As a result, these enzymes constitute attractive targets for modulating the immune system to fight autoimmune disorders and cancer. The EU-funded CAPSTONE project aims to investigate the mechanisms underlying the antigen processing dysfunction encountered in these diseases and the implication of ERAP enzymes. With a long-term goal to develop innovative therapeutic drugs, CAPSTONE will bring together an intersectoral and multidisciplinary group of experts. More importantly, it will train early-stage researchers and prepare them for a career in academia or the pharmaceutical industry.

Call for proposal

H2020-MSCA-ITN-2020
See other projects for this call

Coordinator

UNIVERSITE DE LILLE
Address
42 Rue Paul Duez
59800 Lille
France
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 549 604,08

Participants (9)

"NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS"""
Greece
EU contribution
€ 486 035,28
Address
End Of Patriarchou Grigoriou E And 27 Neapoleos Street
15341 Agia Paraskevi
Activity type
Research Organisations
UNIVERSITY OF SOUTHAMPTON
United Kingdom
EU contribution
€ 606 345,12
Address
Highfield
SO17 1BJ Southampton
Activity type
Higher or Secondary Education Establishments
UNIVERSITE DE PARIS
France
EU contribution
€ 549 604,08
Address
85 Bd Saint Germain
75006 Paris
Activity type
Higher or Secondary Education Establishments
OSPEDALE PEDIATRICO BAMBINO GESU
Italy
EU contribution
€ 522 999,36
Address
Piazza Sant Onofrio 4
00165 Roma
Activity type
Research Organisations
ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON
Greece
EU contribution
€ 243 017,64
Address
6 Christou Lada Str
10561 Athina
Activity type
Higher or Secondary Education Establishments
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
EU contribution
€ 265 619,88
Address
Heidelberglaan 100
3584 CX Utrecht
Activity type
Higher or Secondary Education Establishments
IMABIOTECH SAS
France
EU contribution
€ 274 802,04
Address
152 Rue Du Docteur Yersin
59120 Loos
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
INOCURE SRO
Czechia
EU contribution
€ 234 871,56
Address
Politickych Veznu 935/13
11000 Praha
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
NOVAMECHANICS LIMITED
Cyprus
EU contribution
€ 235 836,72
Address
Digeni Akrita 51
1070 Nicosia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)