Skip to main content

Training network to advance integrated computational simulations in translational medicine, applied to intervertebral disc degeneration

Objective

The European community requires early stage researchers (ESRs) who can work across the boundaries of traditional disciplines, integrating experimental and in silico approaches to understand and manage complex multifactorial disorders. This training network utilises intervertebral disc degeneration (LDD) leading to low back pain (LBP) as a relevant application for data integration and computational simulations in translational medicine. LBP is the largest cause of morbidity worldwide, yet there remains controversy as to the specific cause leading to poor treatment options and prognosis. LDD is reported to account for 50% of LBP in young adults, but the interplay of factors from genetics, environmental, cellular responses and social and psychological factors is poorly understood. Unfortunately, the integration of such data into a holistic and rational map of degenerative processes and risk factors has not been achieved, requiring creation of professional crosscompetencies, which current training programmes fail to address. Disc4All aims to tackle this issue through collaborative expertise of clinicians; computational physicists and biologists; geneticists; computer scientists; cell and molecular biologists; microbiologists; bioinformaticians; and industrial partners. It provides interdisciplinary training in data curation and integration; experimental and theoretical/computational modelling; computer algorithm development; tool generation; and model and simulation platforms to transparently integrate primary data for enhanced clinical interpretations through models and simulations. Complementary training is offered in dissemination; project management; research integrity; ethics; regulation; policy; business strategy; and public and patient engagement. The Disc4All ESRs will provide a new generation of internationally mobile professionals with unique skill sets for the development of thriving careers in translational research applied to multifactorial disorders.

Call for proposal

H2020-MSCA-ITN-2020
See other projects for this call

Funding Scheme

MSCA-ITN-ETN - European Training Networks

Coordinator

UNIVERSIDAD POMPEU FABRA
Address
Placa De La Merce, 10-12
08002 Barcelona
Spain
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 501 809,76

Participants (10)

INSILICOTRIALS TECHNOLOGIES SRL
Italy
EU contribution
€ 261 499,68
Address
Via Flavia 23/1
34178 Trieste
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION
Spain
EU contribution
€ 501 809,76
Address
Calle Jordi Girona 31
08034 Barcelona
Activity type
Research Organisations
OULUN YLIOPISTO
Finland
EU contribution
€ 561 611,52
Address
Pentti Kaiteran Katu 1
90014 Oulu
Activity type
Higher or Secondary Education Establishments
GALGO MEDICAL
Spain
EU contribution
€ 250 904,88
Address
Comte Urgell 143 4B
08036 Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
KING'S COLLEGE LONDON
United Kingdom
EU contribution
€ 303 172,56
Address
Strand
WC2R 2LS London
Activity type
Higher or Secondary Education Establishments
SHEFFIELD HALLAM UNIVERSITY
United Kingdom
EU contribution
€ 303 172,56
Address
Howard Street City Campus
S1 1WB Sheffield
Activity type
Higher or Secondary Education Establishments
FUNDACIO INSTITUT MAR D INVESTIGACIONS MEDIQUES IMIM
Spain
EU contribution
€ 250 904,88
Address
Doctor Aiguader 88
08003 Barcelona
Activity type
Research Organisations
UNIVERSITAET BERN
Switzerland
EU contribution
€ 562 553,28
Address
Hochschulstrasse 6
3012 Bern
Activity type
Higher or Secondary Education Establishments
PROTATOUANS - ETAIREIA EREYNAS VIOTECHNOLOGIAS MONOPROSOPI ETAIREIA PERIORISMENIS EYTHINIS
Greece
EU contribution
€ 243 017,64
Address
Odos Navarchou Votsi 3
16675 Glyfada
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITE DE LIEGE
Belgium
EU contribution
€ 256 320
Address
Place Du 20 Aout 7
4000 Liege
Activity type
Higher or Secondary Education Establishments