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Complex microbial ecosystems multiscale modelling: mechanistic and data driven approaches integration.

Objective

European dairy industry is an important agri-food sector; it represents more than 300,000 jobs and 10 billion € positive trade balance. Five out of the ten top global dairy companies are European and more than 80% of European companies are SMEs. More than 300 cheeses and dairy products are sold all over the world and are protected as geographical indications or traditional specialties. Mastering cheese-ripening processes to avoid sanitary risk and waste, and produce typical cheeses with organoleptic properties valued by the consumers is of economic and social significance. E-MUSE aims to develop innovative modelling methodologies to improve knowledge about complex biological systems and to control and/or predict their evolution by combining artificial intelligence and systems biology. This multidisciplinary strategy integrating genome-scale metabolic models, dynamic modelling methodologies, together with the design of efficient statistical and machine learning tools, will allow analysing of multi-omics data and linking the results to macro-scale properties related to cheese ripening and consumer preference. Bioinformatics has addressed this issue by data mining; however, a gap still exists between the molecular scale information and the macroscopic properties that E-MUSE will contribute to fill. Moreover, in the context of sustainable development, more and more consumers are diversifying their diet and consume plant-based food. Introduction of plant-based proteins in the cheese process brings issues such as bitterness or safety. Modelling strategies from the E-MUSE project will help to target and solve these issues. Finally, E-MUSE will train researchers with multidisciplinary skills in mathematics, bioinformatics and/or biology to design and use innovative multiscale modelling methodologies, with the ultimate outcome of a dynamic modelling software giving researchers a harmonised language to address future research questions about complex biological systems.

Field of science

  • /natural sciences/computer and information sciences/artificial intelligence
  • /agricultural sciences/animal and dairy science/dairy
  • /social sciences/other social sciences/social sciences interdisciplinary/sustainable development
  • /natural sciences/computer and information sciences/data science/data mining

Call for proposal

H2020-MSCA-ITN-2020
See other projects for this call

Funding Scheme

MSCA-ITN-ETN - European Training Networks

Coordinator

INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
Address
Rue De L'universite 147
75338 Paris Cedex 07
France
Activity type
Research Organisations
EU contribution
€ 824 406,12

Participants (9)

UNIVERSITE PAUL SABATIER TOULOUSE III
France
EU contribution
€ 274 802,04
Address
Route De Narbonne 118
31062 Toulouse Cedex 9
Activity type
Higher or Secondary Education Establishments
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 501 809,76
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
STICHTING VU
Netherlands
EU contribution
€ 265 619,88
Address
De Boelelaan 1105
1081 HV Amsterdam
Activity type
Higher or Secondary Education Establishments
KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium
EU contribution
€ 512 640
Address
Oude Markt 13
3000 Leuven
Activity type
Higher or Secondary Education Establishments
UNIVERSITA TA MALTA
Malta
EU contribution
€ 237 955,68
Address
University Campus, Tal-qroqq
2080 Msida
Activity type
Higher or Secondary Education Establishments
NIZO FOOD RESEARCH BV
Netherlands
EU contribution
€ 265 619,88
Address
Kernhemseweg 2
6718 ZB Ede Gld
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA
Italy
EU contribution
€ 261 499,68
Address
Via Zamboni 33
40126 Bologna
Activity type
Higher or Secondary Education Establishments
SZEGEDI TUDOMANYEGYETEM
Hungary
EU contribution
€ 459 430,56
Address
Dugonics Ter 13
6720 Szeged
Activity type
Higher or Secondary Education Establishments
CHR. HANSEN A/S
Denmark
EU contribution
€ 297 522
Address
Boege Alle 10-12
2970 Hoersholm
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)