Nanoparticle-Based Imaging and Therapy of Chronic Pain in the Dorsal Root Ganglia (DRG)

Project Information

PIANO

Grant agreement ID: 956477

DOI

10.3030/956477

Project closed

EC signature date 9 November 2020

Start date 1 March 2021

End date 28 February 2025

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 3 565 136,22

EU contribution

€ 3 565 136,22

Coordinated by

KING'S COLLEGE LONDON
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Other (5)

Researcher declarations submitted
Updated Network-training programme
PIANO website

Creation (and maintenance) of the website, launch social media accounts, project brochures,, Internal Portal on PIANO website etc

Good practices report
Movie

Websites, patent fillings, videos etc. (2)

Press Release on Kick-off meeting

Press Release on Kickoff meeting

Press Release on the Final Results

Publications

Peer reviewed articles (12)

Compartmentalized primary cultures ofdorsal root ganglion neurons to modelperipheral pathophysiological conditions

Author(s): Giorgi, Simona; Lamberti, Angela; Butrón, Laura; Gross-Amat, Olivia; Alarcón-Alarcón, David; Rodríguez-Cañas, Enrique; Fernández-Carvajal, Asia; Ferrer-Montiel, Antonio
Published in: Molecular pain / sage journals, Issue 1, 2023, ISSN 1744-8069
Publisher: BioMed Central
DOI: 10.5281/zenodo.8403549

Chemo-Click: Receptor-Controlled and Bioorthogonal Chemokine Ligation for Real-time Imaging of Drug-Resistant Leukemic B Cells

Author(s): Marco Bertolini, Lorena Mendive-Tapia, Utsa Karmakar, Marc Vendrell
Published in: The Journal of the American Chemical Society, 2024, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.26434/chemrxiv-2024-x08ph

Nonperturbative Fluorogenic Labeling of Immunophilins Enables the Wash-free Detection of Immunosuppressants

Author(s): Marco Bertolini; Lorena Mendive-Tapia; Ouldouz Ghashghaei; Abigail Reese; Charles Lochenie; Anna M. Schoepf; Miquel Sintes; Karolina Tokarczyk; Zandile Nare; Andrew D. Scott; Stephen R. Knight; Advait R. Aithal; Amit Sachdeva; Rodolfo Lavilla; Marc Vendrell
Published in: ACS Central Science, 2024, ISSN 2374-7951
Publisher: American Chemical Society
DOI: 10.1021/acscentsci.3c01590

The multicomponent Passerini reaction as a means of accessing diversity in structure, activity and properties: Soft and hard vanilloid/cannabinoid modulators

Author(s): Angela Lamberti, Marta Serafini, Silvio Aprile, Irene Preet Bhela, Georgia Goutsiou, Emanuela Pessolano, Gregorio Fernandez-Ballester, Antonio Ferrer-Montiel, Rita Maria Concetta Di Martino, Asia Fernandez-Carvajal, Tracey Pirali
Published in: European Journal of Medicinal Chemistry, Issue 279, 2024, Page(s) 116845, ISSN 0223-5234
Publisher: Elsevier BV
DOI: 10.1016/j.ejmech.2024.116845

Hyaluronic Acid-Based Nanosystems for CD44 MediatedAnti-Inflammatory and Antinociceptive Activity

Author(s): Salathia, Saniya; Gigliobianco, Maria Rosa; Casadidio, Cristina; Di Martino, Piera; Censi, Roberta
Published in: International Journal of Molecular Medicine, Issue 24(8), 2023, Page(s) 7286, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24087286

Combinatorial Therapeutic Approaches with Nanomaterial-Based Photodynamic Cancer Therapy

Author(s): Hao, Y.; Chung, C.K.; Yu, Z.F.; Veld, R.H.I.V. 't; Ossendorp, F.A.; Dijke, P. ten; Cruz, L.J.
Published in: Pharmaceutics, 14(1). MDPI, Issue 1, 2022, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14010120

Silencing miR-21-5p in sensory neurons reverses neuropathic allodynia via activation of TGF-β–related pathway in macrophages

Author(s): Zeboudj, L; Sideris-Lampretsas, G; Silva, R; Al-Mudaris, S; Picco, F; Fox, S; Chambers, D; Malcangio, M
Published in: The Journal of Clinical Investigation, Issue 1, 2023, ISSN 0021-9738
Publisher: American Society for Clinical Investigation
DOI: 10.1172/jci164472

Smart probes for optical imaging of T cells and screening of anti-cancer immunotherapies

Author(s): Marco Bertolini, Man Sing Wong, Lorena Mendive-Tapia, Marc Vendrell
Published in: Chemical Society Reviews, 2023, Page(s) 1, ISSN 1460-4744
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/d2cs00928e

Enzyme-Activatable Chemokine Conjugates for In Vivo Targeting of Tumor-Associated Macrophages

Author(s): Nicole D. Barth,Floris J. Van Dalen,Dr. Utsa Karmakar,Marco Bertolini, Lorena Mendive-Tapia,Dr. Takanori Kitamura, Martijn Verdoes,Prof. Marc Vendrell
Published in: Angewandte Chemie (Eng edition), Issue 61(41), 2022, Page(s) e202207508, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202207508

Macrophage to neuron communication via extracellular vesicles in neuropathic pain conditions

Author(s): Francesca Picco, Lynda Zeboudj, Silvia Oggero, Vincenzo Prato, Thomas Burgoyne, Nikita Gamper, Marzia Malcangio
Published in: Heliyon, Issue 11, 2025, Page(s) e41268, ISSN 2405-8440
Publisher: Elsevier
DOI: 10.1016/j.heliyon.2024.e41268

Peripheral gating of mechanosensation by glial diazepam binding inhibitor

Author(s): Xinmeng Li, Arthur Silveira Prudente, Vincenzo Prato, Xianchuan Guo, Han Hao, Frederick Jones, Sofia Figoli, Pierce Mullen, Yujin Wang, Raquel Tonello, Sang Hoon Lee, Shihab Shah, Benito Maffei, Temugin Berta, Xiaona Du, Nikita Gamper
Published in: Journal of Clinical Investigation, Issue 134, 2024, ISSN 1558-8238
Publisher: American Society for Clinical Investigation (ASCI
DOI: 10.1172/jci176227

Versatile One-Pot Synthesis of Hydrophobic Tags by Multicomponent Reactions

Author(s): Federica Carolina Balestrero, Laura Gioiello, Georgia Goutsiou, Sabina Sangaletti, Rita Maria Concetta Di Martino, Fabrizio Condorelli, Ambra A. Grolla, Tracey Pirali
Published in: ACS Omega, Issue 10, 2025, Page(s) 4745-4753, ISSN 2470-1343
Publisher: ACS publications
DOI: 10.1021/acsomega.4c09726