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Nanoparticle-Based Imaging and Therapy of Chronic Pain in the Dorsal Root Ganglia (DRG)

Project description

Nanoparticle-based treatment of neuropathic pain

Chronic neuropathic pain, which results from nerve damage or a malfunctioning nervous system, affects 60 million people worldwide. As current pain killers are only partially effective, new therapies are desirable. The EU-funded PIANO project proposes that local targeted delivery to the dorsal root ganglia (DRG) can optimise pain management and allow monitoring changes of pain transmission under neuropathic pain conditions. PIANO focuses on pain mechanisms at the DRG which contain the cell bodies of specialised neurones that transmit noxious signalling from the periphery to the central nervous system, where pain is perceived. Researchers will identify the DRG involved in pain signalling by the aid of targeted nanoparticles to enable visualisation of pain and inflammation and the delivery of analgesic compounds.

Coordinator

KING'S COLLEGE LONDON
Net EU contribution
€ 303 172,56
Address
Strand
WC2R 2LS London
United Kingdom

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Region
London Inner London — West Westminster
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (10)

ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands
Net EU contribution
€ 531 239,76
Address
Albinusdreef 2
2333 ZA Leiden

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Region
West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO
Italy
Net EU contribution
€ 261 499,68
Address
Duomo 6
13100 Vercelli

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Region
Nord-Ovest Piemonte Vercelli
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
PERCUROS BV
Netherlands
Net EU contribution
€ 531 239,76
Address
Eerbeeklaan 42
2573 HT 'S-gravenhage

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
West-Nederland Zuid-Holland Agglomeratie ’s-Gravenhage
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
UNIVERSITY OF LEEDS
United Kingdom
Net EU contribution
€ 303 172,56
Address
Woodhouse Lane
LS2 9JT Leeds

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Region
Yorkshire and the Humber West Yorkshire Leeds
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITA DEGLI STUDI DI CAMERINO
Italy
Net EU contribution
€ 522 999,36
Address
Piazza Cavour 19f
62032 Camerino

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Region
Centro (IT) Marche Macerata
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
THE UNIVERSITY OF EDINBURGH
United Kingdom
Net EU contribution
€ 606 345,12
Address
Old College, South Bridge
EH8 9YL Edinburgh

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Region
Eastern Scotland Edinburgh
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE
Spain
Net EU contribution
€ 250 904,88
Address
Avenida De La Universidad S-n
03202 Elche

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Region
Este Comunitat Valenciana Alicante/Alacant
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
MEDRES-MEDICAL RESEARCH GMBH
Germany
Net EU contribution
€ 252 788,40
Address
Gleueler Strasse 50
50931 Koln

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nordrhein-Westfalen Köln Köln, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
POLYPURE AS
Norway
Net EU contribution
€ 292 342,32
Address
Gaustadalleen 21
0349 Oslo

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Norge Oslo og Viken Oslo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
CHEMPRECISE CONSULTORIA BIOTECNOLOGIA PRODUTOS FARMACEUTICOS E IMOBILIARIO LDA
Portugal
Net EU contribution
€ 237 720,24
Address
Rua Da Horta Nova 6
2560-654 Torres Vedras

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Continente Centro (PT) Oeste
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00