Project description
A patient-friendly instrument offers high-resolution eye examination
The diagnosis of eye diseases as well as routine eye exams usually involve high-resolution imaging instruments. However, these are expensive and not very patient-friendly, requiring contact with the eye during examination. The scientists of the EU-funded ODYSSEUS project have previously developed a novel technology that allows the live visualisation of the retina and cornea of the eye at cell resolution and without touching the eye. ODYSSEUS will generate a compact instrument for both corneal and retinal examination suitable for use in a clinical environment and validate its performance. This technology is expected to improve the diagnostic accuracy of eye examinations and prevent surgical interventions at late disease stages.
Objective
Non-contact cell-resolution imaging of the whole eye is the Holy Grail of ophthalmic diagnosis. If achieved and wide-spread, it can allow detection of diseases at the very earliest stages, resulting in a prominent positive effect both on society through improving the ocular health in the population, and on economy through reducing the number of costly surgical interventions at the late disease stages and through keeping the population economically active. Several highresolution eye imaging instruments reached the market, however they failed to become wide-spread due to their great complexity, high price (Adaptive optics systems) and not patient-friendly imaging procedure, for example, requiring contact with the eye during examination (Confocal microscopy systems). In a course of ERC HELMHOLTZ project, we for the first time we applied Full-field Optical Coherence Tomography (FFOCT) technology to ophthalmology and built two instruments for corneal and retinal imaging. We demonstrated the unique abilities of FFOCT technology to visualize live retina and cornea of the eye with cell-resolution, in a non-contact way, using a simple optical design without complex adaptive optics. In ODYSSEUS we propose to develop a single combined FFOCT instrument for both corneal and retinal examination. The instrument will be compact, cost-effective, adapted for use in clinical environment and will demonstrate the improved imaging performance, meeting the desires of our partners in the hospital. The developed technology will be transferred to our partners in Vision Institute and the Hospital for clinical studies in patients. In addition, we have filled the first patent on ophthalmic FFOCT and, once the prototype is validated, we plan to create a start-up, specializing in manufacturing and sales of FFOCT-based diagnostic devices for ophthalmology.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine ophthalmology
- medical and health sciences clinical medicine surgery surgical procedures
- natural sciences physical sciences optics microscopy confocal microscopy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
ERC-POC - Proof of Concept Grant
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2020-PoC
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
75231 Paris
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.