Project description
Novel universal vaccine against seasonal flu outbreaks
Seasonal flu and other respiratory RNA viral infections affect ~10 % of the global population every year. Existing prophylactic vaccination has limited efficacy and requires updates each flu season or pandemic outbreak due to the high mutation rate of the viral surface proteins targeted by current vaccines. French clinical-stage biotech OSIVAX aims to develop novel vaccines to prevent respiratory viral infections for multiple seasons and outbreaks. OSIVAX has developed OVX836, a universal flu vaccine candidate based on a proprietary immune-boosting technology that triggers targeted and durable immune responses. OVX836 circumvents the annual vaccination updates by targeting an intraviral protein conserved across all influenza strains. The goal of the EU-funded OSIRIX project is to prepare OVX836 for the clinical proof-of-efficacy milestone.
Fields of science
- medical and health sciencesbasic medicineimmunologyimmunisation
- medical and health scienceshealth sciencesinfectious diseasesRNA virusesinfluenza
- medical and health scienceshealth sciencesinfectious diseasesRNA virusescoronaviruses
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines
Programme(s)
Funding Scheme
SME-2b - SME Instrument (grant only and blended finance)
Coordinator
75008 Paris
France
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