Project description
Attention protein researchers, the fast train carrying labelled amino acids is at the station
Proteins are behind innumerable critical functions in our bodies providing mechanical support and immunity, controlling growth and differentiation, transporting and storing nutrients, and carrying signals. As amino acids are the building blocks of proteins, one of the tricks of the scientific trade in studying processes in health and disease is to label them to facilitate structure determination or to figure out where they go and what they do. Current methods for producing labelled amino acids face synthetic challenges that limit the accessibility of these labelled amino acids, slowing innovation. The EU-funded LABELED AMINO ACIDS project developed a new technology to overcome these barriers. Successful commercialisation of the product will strengthen Europe's leadership, streamline research and development, and open the door to the study of proteins that are currently inaccessible.
Objective
Isotope-labeled amino acids are highly valuable and versatile tools to tackle complex biological questions and to accelerate research and therapeutic development. Current production processes are, however, low-yielding, expensive and time-intensive, and cannot be applied to all amino acids, leading to missed therapeutic opportunities and inefficient use of resources. We have addressed these limitations and developed an innovative and more efficient method to produce such isotope-labeled amino acids. Our new technology is fully scalable, substantially undercuts industry production costs, and provides access to products currently not available.
The main objective of this project is to advance this technology to a commercializable stage that will enable us to distribute these valuable tools globally. This requires further proof-of-concept data and expansion and optimization of our protocols to bring it to industry standards and scale. This, in turn, will strengthen our intellectual property position, which is crucial for establishing a spin-off company. Anticipated outcomes of successful commercialization of our technology include several economic benefits for the EU, strengthening EU’s leadership in biotechnology and innovation, and –most importantly– technological advancements that will create new research avenues, improve research translation and disease management, and lead to an overall improvement of health and well-being.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
ERC-POC - Proof of Concept Grant
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2020-PoC
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1010 WIEN
Austria
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.