An innovative family of antibiotics to fight multi-resistant bacteria

Objective

Antibiotic resistant bacteria are rapidly emerging worldwide. This antibiotic resistance crisis is notably connected to the massive misuse of antibiotics and the lack of novel and efficient compounds. With countless structures and properties, natural products including ribosomally synthesized and post-translationally modified peptides (RiPP) are a promising source of antibiotics . However, their development as effective antibiotics faces many challenges related notably to their synthesis, stability and bioavailability. In the frame of this project, we aim to engineer a novel class of RiPPs in order to develop innovative antibiotics.

Fields of science

• natural sciences › biological sciences › microbiology › bacteriology
• medical and health sciences › basic medicine › pharmacology and pharmacy › drug resistance › antibiotic resistance

Programme(s)

• H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)

Topic(s)

• ERC-2020-POC - Call for proposals for ERC Proof of Concept Grant

Call for proposal

ERC-2020-PoC
See other projects for this call

Funding Scheme

ERC-POC-LS - ERC Proof of Concept Lump Sum Pilot

Host institution

INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT

Address

147 Rue De L'universite
75007 Paris Cedex 07
France

Activity type

Research Organisations

EU contribution

€ 150 000

Beneficiaries (1)

INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT

France

EU contribution

€ 150 000

Address

147 Rue De L'universite
75007 Paris Cedex 07

Activity type

Research Organisations