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A KEY TO THE RATIONAL DESIGN OF EXTRACELLULAR VESICLES-MIMICKING NANOPARTICLES

Project description

Nature's intercellular 'metastasis scouts' teach us how to make nanoparticle therapeutics

Extracellular vesicles (EVs) are one of nature's many cargo trafficking systems, a way to get important materials from one cell to another over short and long distances. They show significant diversity in size, composition and mechanisms related to their functions and fates. Interactions with recipient cells can also have myriad and varied effects. Harnessing all this complexity to deliver therapeutics is no easy task, but the EU-funded MIMIC-KeY project is up to the challenge. The team will profile tumour-derived EVs to better understand how they recognise and target new tissues while performing their role in metastasis. It could lead to the rational design of nanoparticles for therapeutics that mimic nature.

Call for proposal

H2020-FETOPEN-2018-2020

See other projects for this call

Sub call

H2020-FETOPEN-2018-2019-2020-01

Coordinator

POLITECNICO DI TORINO
Net EU contribution
€ 528 987,50
Address
Corso Duca Degli Abruzzi 24
10129 Torino
Italy
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (6)

TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands
Net EU contribution
€ 359 053,75
Address
Groene Loper 3
5612 AE Eindhoven
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
Italy
Net EU contribution
€ 449 875,00
Address
Via Mario Negri 2
20156 Milano
Activity type
Research Organisations
Non-EU contribution
€ 0,00
SCUOLA UNIVERSITARIA PROFESSIONALE DELLA SVIZZERA ITALIANA
Switzerland
Net EU contribution
€ 337 321,25
Address
Stabile Le Gerre
6928 Manno
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITEIT UTRECHT
Netherlands
Net EU contribution
€ 568 790,00
Address
Heidelberglaan 8
3584 CS Utrecht
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA
Spain
Net EU contribution
€ 457 250,00
Address
Passeig Vall D Hebron 119-129 Edificio De Recerca
08035 Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
OXFORD NANOIMAGING LTD
United Kingdom
Net EU contribution
€ 201 250,00
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Linacre House, Banbury Road
OX2 8TA Oxford
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire