Project description
Nature's intercellular 'metastasis scouts' teach us how to make nanoparticle therapeutics
Extracellular vesicles (EVs) are one of nature's many cargo trafficking systems, a way to get important materials from one cell to another over short and long distances. They show significant diversity in size, composition and mechanisms related to their functions and fates. Interactions with recipient cells can also have myriad and varied effects. Harnessing all this complexity to deliver therapeutics is no easy task, but the EU-funded MIMIC-KeY project is up to the challenge. The team will profile tumour-derived EVs to better understand how they recognise and target new tissues while performing their role in metastasis. It could lead to the rational design of nanoparticles for therapeutics that mimic nature.
Fields of science
- natural sciencesphysical sciencesopticsmicroscopysuper resolution microscopy
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteins
- natural sciencesbiological sciencesbiochemistrybiomoleculeslipids
- engineering and technologynanotechnologynano-materials
- natural sciencescomputer and information sciencescomputational sciencemultiphysics
Programme(s)
Funding Scheme
RIA - Research and Innovation actionCoordinator
10129 Torino
Italy
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Participants (6)
5612 AE Eindhoven
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20156 Milano
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6928 Manno
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3584 CS Utrecht
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08035 Barcelona
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OX2 8TA Oxford
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.