Project description
Take a big breath against the coronavirus
The key to beating the spread of the coronavirus is planning and investment in developing means of detection, protection and treatment. Measures aimed at monitoring the dispersion of the coronavirus and fast screening of individuals are vital. There is also an urgent need to rapidly distinguish COVID-19 from other respiratory conditions. In this context, the EU-funded ARIADNE project will propose breath analysis to test for COVID-19. Specifically, it is developing a multiple-stage analytical platform based on multidimensional mass spectrometry instrumentation. It will integrate technological advancements in breath sampling and post-ionisation methods. A smaller and simplified version of this breakthrough platform will also be developed to advance the field of real-time breath analytics.
Objective
The extraordinary ability of the coronavirus to spread in the environment has established the Covid-19 pandemic as the biggest challenge humanity faces in the XXI century. Covid-19 attacks humans regardless of age, claiming the life of over 8,000 people in a single day, with a devastating death toll exceeding 350,000 in just a few months. The virus is likely to survive for the foreseeable future and disperse further, requiring long-term planning and investment in developing means of detection, protection and cure. Protective measures based on monitoring the dispersion of the coronavirus in the environment and fast screening of individuals has become paramount for ensuring safety of our ageing population and restarting/supporting the worldwide economy. The objective of the ARIADNE project is to develop a multiple-stage analytical platform based on multi-dimensional mass spectrometry instrumentation. Performing direct and instant detection of intact virus particles in breath and in water, and going far beyond that task, this unique analytical platform will push the scientific boundaries in all aspects of analytical sciences centered on mass spectrometry, incorporating a series of potentially disruptive technologies integrated into a single system. ARIADNE integrates state-of-the-art technological advancements in breath sampling and post-ionization methods, new analytical tools for characterization of the protein content of viruses by top-down mass spectrometry, non-destructive ultra-high mass analysis of single particles followed by their soft landing and further processing based on advanced single proteomic workflows. A compact and simplified version of this versatile and powerful analytical platform is also envisaged for advancing the field of real-time breath analytics. Applications extending the analytical capabilities of the system to new viruses, intact bacteria as well as whole human cells will also become accessible.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciencesbiological sciencesmicrobiologyvirology
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteins
- medical and health scienceshealth sciencesinfectious diseasesRNA virusescoronaviruses
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Keywords
Programme(s)
Call for proposal
(opens in new window) H2020-FETOPEN-2018-2020
See other projects for this callSub call
H2020-FETOPEN-2018-2019-2020-01
Funding Scheme
RIA - Research and Innovation actionCoordinator
15232 CHALANDRI
Greece
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.