Project description DEENESFRITPL Take a big breath against the coronavirus The key to beating the spread of the coronavirus is planning and investment in developing means of detection, protection and treatment. Measures aimed at monitoring the dispersion of the coronavirus and fast screening of individuals are vital. There is also an urgent need to rapidly distinguish COVID-19 from other respiratory conditions. In this context, the EU-funded ARIADNE project will propose breath analysis to test for COVID-19. Specifically, it is developing a multiple-stage analytical platform based on multidimensional mass spectrometry instrumentation. It will integrate technological advancements in breath sampling and post-ionisation methods. A smaller and simplified version of this breakthrough platform will also be developed to advance the field of real-time breath analytics. Show the project objective Hide the project objective Objective The extraordinary ability of the coronavirus to spread in the environment has established the Covid-19 pandemic as the biggest challenge humanity faces in the XXI century. Covid-19 attacks humans regardless of age, claiming the life of over 8,000 people in a single day, with a devastating death toll exceeding 350,000 in just a few months. The virus is likely to survive for the foreseeable future and disperse further, requiring long-term planning and investment in developing means of detection, protection and cure. Protective measures based on monitoring the dispersion of the coronavirus in the environment and fast screening of individuals has become paramount for ensuring safety of our ageing population and restarting/supporting the worldwide economy. The objective of the ARIADNE project is to develop a multiple-stage analytical platform based on multi-dimensional mass spectrometry instrumentation. Performing direct and instant detection of intact virus particles in breath and in water, and going far beyond that task, this unique analytical platform will push the scientific boundaries in all aspects of analytical sciences centered on mass spectrometry, incorporating a series of potentially disruptive technologies integrated into a single system. ARIADNE integrates state-of-the-art technological advancements in breath sampling and post-ionization methods, new analytical tools for characterization of the protein content of viruses by top-down mass spectrometry, non-destructive ultra-high mass analysis of single particles followed by their soft landing and further processing based on advanced single proteomic workflows. A compact and simplified version of this versatile and powerful analytical platform is also envisaged for advancing the field of real-time breath analytics. Applications extending the analytical capabilities of the system to new viruses, intact bacteria as well as whole human cells will also become accessible. Fields of science natural sciencesbiological sciencesmicrobiologybacteriologynatural sciencesbiological sciencesmicrobiologyvirologynatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsmedical and health scienceshealth sciencesinfectious diseasesRNA virusescoronavirusesnatural scienceschemical sciencesanalytical chemistrymass spectrometry Keywords breath analysis intact viruses intact bacteria mass spectrometry top-down single cell proteomics non-destructive mass analysis Programme(s) H2020-EU.1.2. - EXCELLENT SCIENCE - Future and Emerging Technologies (FET) Main Programme H2020-EU.1.2.1. - FET Open Topic(s) FETOPEN-01-2018-2019-2020 - FET-Open Challenging Current Thinking Call for proposal H2020-FETOPEN-2018-2020 See other projects for this call Sub call H2020-FETOPEN-2018-2019-2020-01 Funding Scheme RIA - Research and Innovation action Coordinator FASMATECH EPISTIMONIKI KAI TECHNOLOGIKI ANONYMI ETAIREIA Net EU contribution € 1 367 500,00 Address PATRIARCHOU GRIGORIOU E KAI NEAPOLEOS, LEFKIPPOS TECHNOLOGY PARK, NCSR DEMOKRITOS, BUILDING 27 153 41 AGIA PARASKEVI Greece See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Αττική Aττική Βόρειος Τομέας Αθηνών Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 1 367 500,00 Participants (7) Sort alphabetically Sort by Net EU contribution Expand all Collapse all KAROLINSKA INSTITUTET Sweden Net EU contribution € 617 000,00 Address Nobels Vag 5 17177 Stockholm See on map Region Östra Sverige Stockholm Stockholms län Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 617 000,00 FOSSIL ION TECHNOLOGY SL Spain Net EU contribution € 495 000,00 Address CALLE CIPRESES 18 28036 Madrid See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 495 000,00 LEIBNIZ-INSTITUT FUR VIROLOGIE Participation ended Germany Net EU contribution € 0,00 Address MARTINISTRASSE 52 20251 Hamburg See on map Region Hamburg Hamburg Hamburg Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS France Net EU contribution € 402 975,00 Address RUE MICHEL ANGE 3 75794 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 452 500,00 Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. UNIVERSITE LYON 1 CLAUDE BERNARD France Net EU contribution € 49 525,00 Address BOULEVARD DU 11 NOVEMBRE 1918 NUM43 69622 Villeurbanne Cedex See on map Region Auvergne-Rhône-Alpes Rhône-Alpes Rhône Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 49 525,00 SPECTROSWISS SARL Switzerland Net EU contribution € 450 000,00 Address EPFL INNOVATION PARK BUILDING I 1015 Lausanne See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Schweiz/Suisse/Svizzera Région lémanique Vaud Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 450 000,00 UNIVERSITAET SIEGEN Germany Net EU contribution € 600 000,00 Address ADOLF REICHWEIN STRASSE 2A 57076 Siegen See on map Region Nordrhein-Westfalen Arnsberg Siegen-Wittgenstein Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 600 000,00
