Redefining mass spectrometry – a breakthrough platform for real-time noninvasive breath analysis with single ion detection of intact viruses and bacteria and post-analysis molecular characterization

Project Information

ARIADNE

Grant agreement ID: 964553

DOI 10.3030/964553

EC signature date 9 March 2021

Start date 1 June 2021

End date 31 May 2025

Funded under

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Total cost € 3 982 000,00

EU contribution € 3 982 000,00

Coordinated by

FASMATECH EPISTIMONIKI KAI TECHNOLOGIKI ANONYMI ETAIREIA
Greece

Deliverables

Documents, reports (4)

Dissemination & Exploitation plan

Dissemination Exploitation plan Report M6

Single bacterial cell proteomics workflow development

KI will report on the development of single bacterial cell proteomics workflows M12

Development of proteomics workflows for analysing viruses

USIEG will report on the development of proteomics workflows for analysing viruses M12

Advancements in single bacterial cell proteomics workflows

KI will report on advancements in single bacterial cell proteomics workflows M30

Open Research Data Pilot (1)

Data Management Plan (DMP)

Open Research Data Pilot Open Access to Scientific Publications

Websites, patent fillings, videos etc. (2)

Scientific reports and publications

D71 Scientific reports and publications M24

Project logo and website launch and public accessibility

Project logo and website launch and public accessibility M4

Demonstrators, pilots, prototypes (2)

Working system in both transmission and trapping modes

CNRS will demonstrate a working system in both transmission and trapping modes (M18).

Omnitrap platform to USIEG for coupling to the UHMR

FAST will deliver an omnitrap platform to USIEG for coupling to the UHMR (M12).

Publications

Peer reviewed articles (4)

Solvent-Induced Aggregation of Self-Assembled Copper–Cysteine Nanoparticles Reacted with Glutathione: Enhancing Linear and Nonlinear Optical Properties

Author(s): Dipankar Bain, Isabelle Russier-Antoine, Hao Yuan, Sarita Kolay, Sylvain Maclot, Christophe Moulin, Estelle Salmon, Pierre-François Brevet, Anna Pniakowska, Joanna Olesiak-Bańska and Rodolphe Antoine
Published in: Langmuir 2023, 39, 46, 16554–16561, 2023, ISSN 1520-5827
Publisher: ACSPublications
DOI: 10.1021/acs.langmuir.3c02526

Super-Resolution Mass Spectrometry Enables Rapid, Accurate, and Highly Multiplexed Proteomics at the MS2 Level

Author(s): Anton N. Kozhinov, Alex Johnson, Konstantin O. Nagornov, Michael Stadlmeier, Warham Lance Martin, Loïc Dayon, John Corthésy, Martin Wühr, and Yury O. Tsybin
Published in: Analytical Chemistry, 2023, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.2c04742

Structural Analysis of Monoclonal Antibodies with Top-down and Middle-down Electron Transfer Dissociation Mass Spectrometry: The First Decade

Author(s): Luca Fornelli, Daniel Ayoub, Kristina Srzentic, Konstantin O. Nagornov, Anton N. Kozhinov, Natalia Gasilova, Laure Menin, Alain Beck, Yury O. Tsybin
Published in: Chimia, 2022, ISSN 0009-4293
Publisher: Schweizerische Chemische Gedellschaft
DOI: 10.2533/chimia.2022.114

Toward Single Bacterium Proteomics

Author(s): Ákos Végvári, Xuepei Zhang, Roman A. Zubarev
Published in: J. Am. Soc. Mass Spectrom. 2023, 34, 2098−2106, 2023, ISSN 1044-0305
Publisher: Elsevier BV
DOI: 10.1021/jasms.3c00242

Book chapters (1)

Physical VirologyFrom the State-of-the-Art Research to the Future of Applied VirologyChapter 9Norovirus - A capsid in perpetual flux

Author(s): Lars Thiede, Ronja Pogan, Charlotte Uetrecht
Published in: 2023, ISBN 978-3-031-36814-1
Publisher: SPRINGER
DOI: 10.1007/978-3-031-36815-8