European Clinical Research Alliance on Infectious Diseases

Informations projet

ECRAID-Base

N° de convention de subvention: 965313

DOI

10.3030/965313

Date de signature de la CE 29 Janvier 2021

Date de début 1 Mars 2021

Date de fin 28 Février 2026

Financé au titre de

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Coût total

€ 29 969 875,00

Contribution de l’UE

€ 29 969 875,00

Coordonné par

STICHTING EUROPEAN CLINICAL RESEARCH ALLIANCE ON INFECTIOUS DISEASES
Netherlands

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (2)

Updated ECRAID business plan

Updated ECRAID business plan month 12 annually updated

Virtual learning Platform

Updated Virtual learning Platform

Websites, patent fillings, videos etc. (1)

Project website and social media accounts

Project website and social media accounts month 3

Open Research Data Pilot (1)

Communications overview report

Communications overview report month 12 annually updated including overview of leaflets newsletters conferences brochures videos and other communications

Publications

Peer reviewed articles (17)

Heterogeneous Treatment Effects of Therapeutic-Dose Heparin in Patients Hospitalized for COVID-19.

Auteurs: Ewan C. Goligher, MD, PhD; Patrick R. Lawler, MD, MPH; Thomas P. Jensen, MS; et al
Publié dans: JAMA, 2023, ISSN 1538-3598
Éditeur: American Medical Association
DOI: 10.1001/jama.2023.3651

Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial.

Auteurs: Writing Committee for the REMAP-CAP Investigators; Patrick R Lawler, Lennie P G Derde, Frank L van de Veerdonk, Bryan J McVerry, David T Huang, Lindsay R Berry, Elizabeth Lorenzi, Roland van Kimmenade, Frank Gommans, Muthiah Vaduganathan, David E Leaf, Rebecca M Baron, Edy Y Kim, Claudia Frankfurter, Slava Epelman, Yvonne Kwan, Richard Grieve, Stephen O'Neill, Zia Sadique, Michael Puskarich, John
Publié dans: JAMA, 2023, ISSN 1538-3598
Éditeur: American Medical Association
DOI: 10.1001/jama.2023.4480

Simvastatin in Critically Ill Patientswith Covid-19

Auteurs: The REMAP-CAP Investigators
Publié dans: The New England Journal of Medicine, 2023, ISSN 1533-4406
Éditeur: Massachusetts Medical Society
DOI: 10.1056/nejmoa2309995

Platform trials as the way forward in infectious disease' clinical research: the case of coronavirus disease 2019.

Auteurs: Juan M Pericàs, Lennie P G Derde, Scott M Berry; EU-PEARL and REMAP-CAP investigators
Publié dans: Clinical Microbiolology and Infection, 2023, ISSN 1469-0691
Éditeur: Elsevier
DOI: 10.1016/j.cmi.2022.11.022

Perpetual observational studies: new strategies to support efficient implementation of observational studies and randomized trials in infectious diseases

Auteurs: NasreenHassoun-Kheir1C. Henrivan Werkhoven2 JakeDunning3 ThomasJaenisch4 Jankovan Beek5 JuliaBielicki67 Christopher C.Butler8 BrunoFrancois9 StephanHarbarth1 Ana C.Hernandez Padilla9 PeterHorby3 MarionKoopmans510 JamesLee3 JesúsRodriguez-Baño1112 EvelinaTacconelli13 YreneThemistocleous3 Alike W.van der Velden2 MarcBonten2 HermanGoossens14 Marlieke E.A.de Kraker1 on behalf of ECRAID-Base consort
Publié dans: Clinical Microbiology and Infection, 2022, ISSN 1198-743X
Éditeur: Blackwell Publishing Inc.
DOI: 10.1016/j.cmi.2022.07.024

The Renin-Angiotensin System in Acute Lung Injury

Auteurs: Patrick R Lawler, Lennie P G Derde, Bryan J McVerry, James A Russell, Frank L van de Veerdonk
Publié dans: Critical Care Medicine, 2022, ISSN 1530-0293
Éditeur: Lippincott Williams & Wilkins on behalf of the Society of Critical Care Medicine
DOI: 10.1097/ccm.0000000000005567

EPI-Net One Health reporting guideline for antimicrobialconsumption and resistance surveillance data: a Delphi approach

Auteurs: Babu Rajendran N, Arieti F, Mena-Benítez CA, Galia L, Tebon M, Alvarez J, Gladstone BP, Collineau L, De Angelis G, Duro R, Gaze W, Göpel S, Kanj SS, Käsbohrer A, Limmathurotsakul D, Lopez de Abechuco E, Mazzolini E, Mutters NT, Pezzani MD, Presterl E, Renk H, Rodríguez-Baño J, Săndulescu O, Scali F, Skov R, Velavan TP, Vuong C, Tacconelli E; EPI-Net One Health consensus working group.
Publié dans: The Lancet Regional Health - Europe, 2023, ISSN 1474-547X
Éditeur: Elsevier
DOI: 10.1016/j.lanepe.2022.100563

Are monoclonals the way forward to prevent or to treat ventilator-associated pneumonia in the intensive care unit?

Auteurs: Ana Catalina Hernandez Padilla, Sylvain Meyer, CH Van Werkhoven, Marlieke EA de Kraker, Bruno François
Publié dans: Expert Opinion on Biological Therapy, 2023, ISSN 1744-7682
Éditeur: Taylor & Francis
DOI: 10.1080/14712598.2023.2240701

Continuation of therapeutic dose heparin for critically ill patients with COVID-19.

Auteurs: Charlotte A. Bradbury, Patrick R. Lawler, Bryan J. McVerry & Ryan Zarychanski on behalf of the REMAP-C. A. P. Investigators
Publié dans: Intensive care medicine, 2023, ISSN 1432-1238
Éditeur: Springer Science+Business Media
DOI: 10.1007/s00134-023-07095-8

Case numbers of acute hepatitis of unknown aetiology among children in 24 countries up to 18 April 2022 compared to the previous 5 years

Auteurs: Janko van Beek Pieter LA Fraaij Carlo Giaquinto Delane Shingadia Peter Horby Giuseppe Indolfi Marion Koopmans Acute hepatitis study group
Publié dans: Eurosurveillance, 2022, ISSN 1025-496x
Éditeur: Centre Europeen pour la Surveillance Epidemiologique du SIDA
DOI: 10.2807/1560-7917.es.2022.27.19.2200370

Low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals

Auteurs: Luca M. Zaeck, Mart M. Lamers, Babs E. Verstrepen, Theo M. Bestebroer, Martin E. van Royen, Hannelore Götz, Marc C. Shamier, Leanne P.M. van Leeuwen, Katharina S. Schmitz, Kimberley Alblas, Suzanne van Efferen, Susanne Bogers, Sandra Scherbeijn, Guus F. Rimmelzwaan, Eric C.M. van Gorp, Marion P.G. Koopmans, Bart L. Haagmans, Corine H. GeurtsvanKessel, Rory D. de Vries
Publié dans: Nature Medicine, 2022, ISSN 1078-8956
Éditeur: Nature Publishing Group
DOI: 10.1101/2022.08.31.22279414

International platform trials: as diseases cross borders, so should trials.

Auteurs: Hiroki Saito on behalf of theRandomized, Embedded, Multifactorial Adaptive Platform trial for Community-Acquired Pneumonia (REMAP-CAP) investigators
Publié dans: The Lancet Infectious Diseases, 2023, ISSN 1474-547X
Éditeur: Elsevier
DOI: 10.1016/s1473-3099(23)00193-7

Coronavirus disease 2019 subphenotypes and differential treatment response to convalescent plasma in critically ill adults: secondary analyses of a randomized clinical trial.

Auteurs: M Fish, J Rynne, A Jennings, C Lam, A A Lamikanra, J Ratcliff, S Cellone-Trevelin, E Timms, J Jiriha, I Tosi, R Pramanik, P Simmonds, S Seth, J Williams, A C Gordon, J Knight, D J Smith, J Whalley, D Harrison, K Rowan, H Harvala, P Klenerman, L Estcourt, D K Menon, D Roberts, M Shankar-Hari; REMAP-CAP Immunoglobulin Domain UK Investigators
Publié dans: Intensive care medicine, 2022, ISSN 1432-1238
Éditeur: Springer Science+Business Media
DOI: 10.1007/s00134-022-06869-w

Enforcing surveillance of antimicrobial resistance and antibiotic use to drive stewardship: experience in a paediatric setting

Auteurs: Zaffagnini A, Rigotti E, Opri F, Opri R, Simiele G, Tebon M, Sibani M; ENSURE Working Group; Piacentini G, Tacconelli E, Carrara E
Publié dans: Journal of Hospital Infection, 2023, ISSN 1532-2939
Éditeur: Elsevier
DOI: 10.1016/j.jhin.2023.12.001

Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial

Auteurs: Authors/Members of the Writing Committee for the REMAP-CAP Investigators: Alisa M. Higgins, PhD; Lindsay R. Berry, PhD; Elizabeth Lorenzi, PhD; Srinivas Murthy, MD; Zoe McQuilten, PhD; Paul R. Mouncey, MSc; Farah Al-Beidh, PhD; Djillali Annane, MD, PhD; Yaseen M. Arabi, MD; Abi Beane, PhD; Wilma van Bentum-Puijk, MSc; Zahra Bhimani, MPH; Marc J. M. Bonten, MD, PhD; Charlotte A. Bradbury, MD, PhD;
Publié dans: JAMA, 2023, ISSN 1538-3598
Éditeur: American Medical Association
DOI: 10.1001/jama.2022.23257

Intravenous Vitamin C for Patients Hospitalized With COVID-19Two Harmonized Randomized Clinical Trials

Auteurs: The LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and the REMAP-CAP Investigators
Publié dans: JAMA, 2023, ISSN 1538-3598
Éditeur: American Medical Association
DOI: 10.1001/jama.2023.21407

Modelling antimicrobial resistance transmission to guide personalized antimicrobial stewardship interventions and infection control policies in healthcare setting: a pilot study

Auteurs: Durazzi F, Pezzani MD, Arieti F, Simonetti O, Canziani LM, Carrara E, Barbato L, Onorati F, Remondini D, Tacconelli E
Publié dans: Scientific Reports, 2023, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-023-51051-x