Project description
AI-based optogenetic microscopy for interactive brain analysis
Brain activity is the result of complex interactions of large populations of neurons located in different regions. Understanding the connection between brain activation and behaviour outcome requires specific experimental strategies to record and externally control neuronal activity. The EU-funded DAPTOMIC project aims to validate the commercial viability of innovative autonomous microscope additions designed for brain imaging. The main objective is to commercialise the modules developed by the EU-funded BrainBIT project. The ensuing AI-based add-on devices will enable the current-generation microscopes to implement the imaging strategy by targeting the sample to image and the portion of the sample to use for interactive analysis.
Objective
Brain activity relies on complex interactions among large populations of neurons located in different brain regions. Understanding the relationships between these specific areas and disentangling the contributions of individual neurons to circuit function is an essential step to understand brain functioning. To elucidate the connection between brain activation and behaviour outcome, it is necessary to establish specific experimental strategies that allow to record and externally control neuronal activity during behaviour. Currently, there is an experimental trade-off between imaging speed, field of view and sample dimensions that limits current recording technology in imaging very large neuronal populations with concurrently high spatial and temporal resolution. Consequently, interactions between neurons in different brain areas are easily missed, whilst functionally related ensembles of neurons can be undetectable, blinded or falsely interpreted. DAPTOMIC aims to demonstrate the commercial viability of a new generation of autonomous (i.e. self-run, similar to a Tesla car) microscope add-on suitable for brain imaging. The main objective of DAPTOMIC is to turn the modules developed within the ERC Advanced Grant BrainBIT into a commercial product (minimum viable product), i.e. a new add-on to current generation microscopes that decides the imaging strategy - which portion of the sample to image and which portion of the sample to interact with – through AI, shortening experiment times by several orders of magnitude.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology
- natural sciences biological sciences molecular biology molecular neuroscience
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
ERC-POC - Proof of Concept Grant
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2020-PoC
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
50121 Florence
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.