Objective The goal of this project is to reduce the faecal excretion, carcass and internal and external egg contamination of Salmonella in chickens. Poultry products are indeed a major source of food-borne salmonellosis for human beings today and therefore constitute a significant public health hazard. It has a highly deleterious effect on the public perception of poultry production if an accident occurs. The way to achieve this goal is the selection of poultry lines resistant to Salmonella infection. Salmonella resistance will be chosen as a start since resistance to this bacteria has already been established in chickens. Faecal and genital routes of Salmonella transmission will be supposed to have different genetic determinants involving either a major gene or polygenes. The search for the genes involved can be helped by knowledge acquired in mice where a Salmonella resistance gene has already been described. In order to avoid deleterious effects on other economic traits, particular attention will be given to the eventual negative impact of resistance and major quantitative traits such as egg and meat production. Common resistance to other bacteria will also be studied to try to broaden the effect of selection. Moreover poultry may constitute a relevant model for other animal species. Fields of science medical and health scienceshealth sciencespublic healthnatural sciencesbiological sciencesmicrobiologybacteriology Programme(s) FP3-AIR - Specific research and technological development and demonstration programme (EEC) in the field of agriculture and agro-industry, including fisheries, 1990-1994 Topic(s) 233 - Genetics and breeding Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator Institut National de la Recherche Agronomique (INRA) Address Centre de tours 37380 Nouzilly France See on map EU contribution No data Participants (5) Sort alphabetically Sort by EU Contribution Expand all Collapse all CENTRE REGIONAL D'INNOVATION ET DE TRANSFERT ET DE TECHNOLOGIE HYGINOV France EU contribution € 0,00 Address 2 bis boulevard tonnele 37000 Tours See on map Other funding No data CNEVA France EU contribution € 0,00 Address Beausemaine 22440 Ploufragen See on map Other funding No data ID-DLO Netherlands EU contribution € 0,00 Address Spelderholt p.0. box 15 7360 AA Beekbergen See on map Other funding No data INSTITUTE FOR ANIMAL HEALTH United Kingdom EU contribution € 0,00 Address High street,compton RG20 7NN Newbury See on map Other funding No data Syndicat des Selectionneurs Avicoles et Aquacoles Français France EU contribution € 0,00 Address 37380 Nouzilly See on map Other funding No data