GENETIC AND BIOCHEMICAL BASIS OF RADIATION SENSITIVITY IN HUMAN AND OTHER MAMMALIAN CELLS IN CULTURE

Project Information

Grant agreement ID: BI6*0169

Project closed

Start date 1 July 1985

End date 31 December 1989

Funded under

• Multiannual research and training programme (Euratom) in the field of radiation protection, 1985-1989

Total cost € 0,00

EU contribution No data

Coordinated by

RIJKSUNIVERSITEIT LEIDEN
Netherlands

Objective

The result of the research supported the previous observation, that the ER response was somehow correlated with the induction of cancer. To study this correlation further, the ER response was determined in ultraviolet (UV) irradiated skin fibroblast from hereditary cancer prone syndromes. Interestingly, much higher levels of ER were observed in all these syndromes than in normal human skin fibroblast.
3. DNA REPAIR AND MUTAGENESIS.

EXPECTED BENEFITS

EVALUATION OF GENETIC RISKS FROM IONIZING RADIATION. DETERMINATION OF CELLULAR RADIOSENSITIVITY AND RELATION TO REPAIR.

Fields of science

• natural sciences › biological sciences › genetics › DNA
• natural sciences › physical sciences › nuclear physics
• medical and health sciences › clinical medicine › oncology

Programme(s)

• FP1-RADPROT 6C - Multiannual research and training programme (Euratom) in the field of radiation protection, 1985-1989

Topic(s)

Data not available

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

RIJKSUNIVERSITEIT LEIDEN

• EU contribution: No data
• Address: STATIONSWEG 46 ; 2300 RA LEIDEN ; Netherlands
• Total cost: No data