GENETIC AND BIOCHEMICAL BASIS OF RADIATION SENSITIVITY IN HUMAN AND OTHER MAMMALIAN CELLS IN CULTURE

Información del proyecto

Identificador del acuerdo de subvención: BI6*0169

Proyecto cerrado

Fecha de inicio 1 Julio 1985

Fecha de finalización 31 Diciembre 1989

Financiado con arreglo a

• Multiannual research and training programme (Euratom) in the field of radiation protection, 1985-1989

Coste total € 0,00

Aportación de la UE Sin datos

Coordinado por

RIJKSUNIVERSITEIT LEIDEN
Netherlands

Objetivo

The result of the research supported the previous observation, that the ER response was somehow correlated with the induction of cancer. To study this correlation further, the ER response was determined in ultraviolet (UV) irradiated skin fibroblast from hereditary cancer prone syndromes. Interestingly, much higher levels of ER were observed in all these syndromes than in normal human skin fibroblast.
3. DNA REPAIR AND MUTAGENESIS.

EXPECTED BENEFITS

EVALUATION OF GENETIC RISKS FROM IONIZING RADIATION. DETERMINATION OF CELLULAR RADIOSENSITIVITY AND RELATION TO REPAIR.

Ámbito científico

• natural sciences › biological sciences › genetics › DNA
• natural sciences › physical sciences › nuclear physics
• medical and health sciences › clinical medicine › oncology

Programa(s)

• FP1-RADPROT 6C - Multiannual research and training programme (Euratom) in the field of radiation protection, 1985-1989

Tema(s)

Data not available

Convocatoria de propuestas

Data not available

Régimen de financiación

CSC - Cost-sharing contracts

Coordinador

RIJKSUNIVERSITEIT LEIDEN

• Aportación de la UE: Sin datos
• Dirección: STATIONSWEG 46 ; 2300 RA LEIDEN ; Países Bajos
• Coste total: Sin datos