Objective
The overall project is based on the study of mouse models generated with the gene targeting and the transgenic technology in order to investigate the mechanism of immune responsiveness and unresponsiveness relevant to autoimmunity.
Studies on the following mouse models have been carried out:
1) Lysozyme transgenic mice.
2) TcR (anti-IgG2a{b}) transgenic mice.
3) beta2-microglobulin gene deficient mice.
4) A CD3-epsilon gene deficient mice.
5) Cell type specific Cre recombinase gene transgenic mice; cytokine receptor gene mutants carrying 'floxed gene' for conditional knock out mice.
1) Tg mouse model of controlled autoimmune disease
2) Tg mouse model of class II restricted self antigen (Ig) presentation
3) A mouse model of Th1/Th2 polarization
4) A CD3 mutated mouse model for thymic selection
5) New cre-recombinase Tg mouse lines useful for the application of somatic gene alteration.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Data not available
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
75724 PARIS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.