Objective
Objectives and content:
The aim of the project is to develop living tissue-engineered bone substitute materials that can replace load-bearing and non load-bearing bone. The proposed material comprises autologous human tissue that is cultured in a three-dimensional biodegradable polymer scaffold, based on starch blends in the case of load-bearing bone, and on PEO/PBT copolymers in the case of non-load-bearing bone. In this project, a hybrid technology will be developed through a combination of biotechnology (development and characterisation of bone cell culture systems) and material technology (development of three-dimensional biodegradable polymeric matrices that facilitate bone cell growth and have similar mechanical properties to either load-bearing or non load-bearing bone). This hybrid technology will allow the production of a laboratory made tissue-engineered living bone equivalent that will exhibit similar mechanical, chemical and biological properties to normal human bone tissue. This novel technology is therefore expected to diminish the shortcomings of all current artificial bone replacement materials.
The consortium is composed of 7 partners that are specialised in, respectively, cell culture techniques (ISOTIS B.V.) starch-based polymers (Novamont SpA), PEO/PBT copolymers (Twente University), non-conventional processing techniques for polymers materials (Cinpres Ltd.), designing techniques in polymeric matrices (Brunel University), material characterisation techniques and polymer bioactivity enhancement (INEB), and compounding and processing techniques of bioactive polymer composites (University of Minho).BE97-4612
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- engineering and technology materials engineering composites
- natural sciences chemical sciences polymer sciences
- medical and health sciences medical biotechnology implants artificial bone
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
3723 MB BILTHOVEN
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.