Objective
The main objective of the research is to Clone, determine the nucleotide sequence, and express in transgenic plants the genes of higher plants coding for proteins binding specifically 2'-5' oligoadenylates (2-5A), in order to investigate their role in defense. They are probably involved in plant response against viral attack, and overexpression of these proteins in transgenic plants, alone or together with 2-5A synthetase, might confer resistance to viruses. The mammalian enzyme has already expressed in higher plants by the project proposers. Tomato and Arabidopsis CDNA (and genomic) libraries will be obtained from other laboratories involved in the network.
The second aim of the proposal is to construct plants which display tolerance to virus infections, using cDNAs of plant 2-5A-binding proteins, isolated from tomato and/or Arabidopsis. In this way it may be possible to obtain transgenic plants which are simultaneously protected against many different plant viruses. This is of special interest with some important crop plants such as tomato and potato, which suffer from simultaneous infections of many different kinds of viruses or viroids.
Fields of science (EuroSciVoc)
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
31326 AUREVILLE
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.