Cel The main objective of the research is to Clone, determine the nucleotide sequence, and express in transgenic plants the genes of higher plants coding for proteins binding specifically 2'-5' oligoadenylates (2-5A), in order to investigate their role in defense. They are probably involved in plant response against viral attack, and overexpression of these proteins in transgenic plants, alone or together with 2-5A synthetase, might confer resistance to viruses. The mammalian enzyme has already expressed in higher plants by the project proposers. Tomato and Arabidopsis CDNA (and genomic) libraries will be obtained from other laboratories involved in the network. The second aim of the proposal is to construct plants which display tolerance to virus infections, using cDNAs of plant 2-5A-binding proteins, isolated from tomato and/or Arabidopsis. In this way it may be possible to obtain transgenic plants which are simultaneously protected against many different plant viruses. This is of special interest with some important crop plants such as tomato and potato, which suffer from simultaneous infections of many different kinds of viruses or viroids. Program(-y) IC-PECO/COPERNICUS - Scientific and technological cooperation between the European Community and European non-member countries, 1992- Temat(-y) 0401 - CEEC participation in HUMAN CAPITAL & MOBILITY programme (NETWORKS) Zaproszenie do składania wniosków Data not available System finansowania CSC - Cost-sharing contracts Koordynator CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE Wkład UE Brak danych Adres Chemin de Borde-Rouge INRA 31326 AUREVILLE Francja Zobacz na mapie Koszt całkowity Brak danych Uczestnicy (1) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko NATIONAL INSTITUTE OF CHEMICAL PHYSICS AND BIOPHYSICS Estonia Wkład UE Brak danych Adres 23,Akademia Tee 23 12618 TALLINN Zobacz na mapie Koszt całkowity Brak danych
