Objective
Hydroxyapatite coated titanium base prostheses are directly implanted without cement in steadly growing numbers but, in spite of varius boneimplant attachment philosophies, little is yet known on the long term service behaviours : at the same time countries such as France are establishing new legislations and standarized tests, in order to verify the observance by the prostheses manufacturers of their claims and specifications and in further phase in order to eliminate from the market the types of prostheses having poorly performed from the clinical point of view.
In this project several hip and dental prostheses manufacturers and a coating service intend to increase their expertise in characterising and controlling their production and to deepen their knowledge on the mechanical and biological behaviour of prostheses coated in air and in low pressure by different types of plasma sprayed hydroxyapatites.
The innovative aspect of the coating developed in this project is the possibility to produce a more stable "Low Fluoro content Hydroxyapatite material" using a Fluoridated-apatite with only 50% of Fluoro content or treating the surface of an improved regular Hydroxiapatite with a fluoridating agent.
In addition a surface treatment has been developed that produces a bioresorbable highly bioactive layer at the surface of the Fluorided-apatite coating in order to enhance its bone formation capability.
The new coatings coupled with the surface treatment should confer better biological and mechanical properties to the coating and a higher performance to the prostheses, improving in vivo stability and bioactivity combined with a good biocompatibility. They show characteristics of biological compatibility and long term stability better than the uncoated or coated with the standard Hydroxyapatite implant.
This effort will also be a necessary preliminary step for the development of various types of prostheses with high quality and long term performances, thanks to mechanically and physiologically stable highly cristalline hydroxyapatites coatings, at the same time surface treated in order to substantially accellerate the bone ongrowth on the implants.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences inorganic chemistry transition metals
- engineering and technology materials engineering coating and films
- medical and health sciences medical biotechnology implants
- humanities philosophy, ethics and religion philosophy
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Coordinator
43045 Fornovo Taro Parma
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.