Objectif
Hydroxyapatite coated titanium base prostheses are directly implanted without cement in steadly growing numbers but, in spite of varius boneimplant attachment philosophies, little is yet known on the long term service behaviours : at the same time countries such as France are establishing new legislations and standarized tests, in order to verify the observance by the prostheses manufacturers of their claims and specifications and in further phase in order to eliminate from the market the types of prostheses having poorly performed from the clinical point of view.
In this project several hip and dental prostheses manufacturers and a coating service intend to increase their expertise in characterising and controlling their production and to deepen their knowledge on the mechanical and biological behaviour of prostheses coated in air and in low pressure by different types of plasma sprayed hydroxyapatites.
The innovative aspect of the coating developed in this project is the possibility to produce a more stable "Low Fluoro content Hydroxyapatite material" using a Fluoridated-apatite with only 50% of Fluoro content or treating the surface of an improved regular Hydroxiapatite with a fluoridating agent.
In addition a surface treatment has been developed that produces a bioresorbable highly bioactive layer at the surface of the Fluorided-apatite coating in order to enhance its bone formation capability.
The new coatings coupled with the surface treatment should confer better biological and mechanical properties to the coating and a higher performance to the prostheses, improving in vivo stability and bioactivity combined with a good biocompatibility. They show characteristics of biological compatibility and long term stability better than the uncoated or coated with the standard Hydroxyapatite implant.
This effort will also be a necessary preliminary step for the development of various types of prostheses with high quality and long term performances, thanks to mechanically and physiologically stable highly cristalline hydroxyapatites coatings, at the same time surface treated in order to substantially accellerate the bone ongrowth on the implants.
Champ scientifique (EuroSciVoc)
CORDIS classe les projets avec EuroSciVoc, une taxonomie multilingue des domaines scientifiques, grâce à un processus semi-automatique basé sur des techniques TLN.
CORDIS classe les projets avec EuroSciVoc, une taxonomie multilingue des domaines scientifiques, grâce à un processus semi-automatique basé sur des techniques TLN.
- sciences naturellessciences chimiqueschimie inorganiquemétal de transition
- ingénierie et technologieingénierie des materiauxrevêtement et films
- sciences médicales et de la santébiotechnologie médicaleimplant
- lettresphilosophie, éthique et religionphilosophie
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Thème(s)
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43045 Fornovo Taro Parma
Italie