Objective The project approach is to carry out laboratory research aimed at establishing the relationship between dehalogenation mechanisms for natural and synthetic organohalogen compounds. Subsequently, it will be investigated which genetic processes (mutation, genetransfer) occur during adaptation under selective conditions, and how these processes are influenced by environmental conditions. The activities include: -isolation of organisms that degrade halogenated substrates, using as inocula samples obtained from unpolluted areas and contaminated sites -physiological and biochemical studies to determine dehalogenation and halogenation mechanisms in newly isolated strains -analysis of the genetic organization of organisms that degrade xenobiotic halogenated compounds -examination of genetic processes that occur in chemostats or biofilm systems and that lead to an expansion of the substrate range of the organisms. Organisms known to degrade natural or synthetic gene transfer and adaptation of the community will be established -testing the effect of environmental conditions on the development of dehalogenating organisms and community adaptation, and establishing the relevance to bioremediation strategies. Fields of science engineering and technologyenvironmental biotechnologybioremediationnatural sciencesbiological sciencesgeneticsmutationnatural sciencesbiological sciencesecologyecosystemsnatural scienceschemical sciencesinorganic chemistryhalogensnatural scienceschemical sciencesorganic chemistryorganohalogen compounds Programme(s) FP4-ENV 2C - Specific programme of research and technological development in the field of environment and climate, 1994-1998 Topic(s) 02020306 - Rehabilitation of contaminated sites Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator Rijksuniversiteit Groningen Address 4,nijenborgh 4 9747 AG Groningen Netherlands See on map EU contribution € 0,00 Participants (3) Sort alphabetically Sort by EU Contribution Expand all Collapse all THE QUEEN'S UNIVERSITY OF BELFAST United Kingdom EU contribution € 0,00 Address Stranmillis road, david keir building BT9 5AG Belfast See on map Technische Universität Dresden Germany EU contribution € 0,00 Address 4,mommsenstrasse 4 01062 Dresden See on map University of Wales Cardiff United Kingdom EU contribution € 0,00 Address CF1 3TL Cardiff See on map