Objective
The project approach is to carry out laboratory research aimed at establishing the relationship between
dehalogenation mechanisms for natural and synthetic organohalogen compounds. Subsequently, it will be
investigated which genetic processes (mutation, genetransfer) occur during adaptation under selective conditions,
and how these processes are influenced by environmental conditions. The activities include:
-isolation of organisms that degrade halogenated substrates, using as inocula samples obtained from
unpolluted areas and contaminated sites
-physiological and biochemical studies to determine dehalogenation and halogenation mechanisms in
newly isolated strains
-analysis of the genetic organization of organisms that degrade xenobiotic halogenated compounds
-examination of genetic processes that occur in chemostats or biofilm systems and that lead to an
expansion of the substrate range of the organisms. Organisms known to degrade natural or synthetic
gene transfer and adaptation of the community will be established -testing the effect of environmental conditions on the development of dehalogenating organisms and
community adaptation, and establishing the relevance to
bioremediation strategies.
Fields of science
- engineering and technologyenvironmental biotechnologybioremediation
- natural sciencesbiological sciencesgeneticsmutation
- natural sciencesbiological sciencesecologyecosystems
- natural scienceschemical sciencesinorganic chemistryhalogens
- natural scienceschemical sciencesorganic chemistryorganohalogen compounds
Call for proposal
Data not availableFunding Scheme
CSC - Cost-sharing contractsCoordinator
9747 AG Groningen
Netherlands
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Participants (3)
BT9 5AG Belfast
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01062 Dresden
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CF1 3TL Cardiff
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