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Content archived on 2019-03-15

CYTOGENETIC RESEARCH TO INVESTIGATE SOMATIC AND GERMINAL DAMAGE

Objective

ELABORATION AND COMPARATIVE EVALUATION OF TEST SYSTEMS FOR THE ASSESSMENT OF GENETIC EFFECTS OF ENVIRONMENTAL CHEMICALS AND OF THE PRODUCTS OF THEIR METABOLIC TRANSFORMATION.

THE AIM OF THIS PROJECT IS TO STUDY THE CYTOGENETIC DAMAGE (SISTER-CHROMATID EXCHANGES AND CHROMOSOMAL ABERRATIONS) INDUCED BY VARIOUS CONCENTRATIONS OF DIRECT AND INDIRECT-ACTING CHEMICAL MUTAGENS ON PROLIFERATING TISSUES (BONE-MARROW, SPLEEN AND SPERMATOGONIA) AND LYMPHOCYTES STIMULATED IN VITRO OF MICE TREATED IN VIVO. PARTICULAR ATTENTION WILL BE GIVEN TO THE DIFFERENT SENSITIVITY OF GERMINAL TISSUES IN RESPECT TO SOMATIC ONES TRYING TO CORRELATE THIS DIFFERENCE TO THE METABOLISM OF THE MUTAGENS AND THE REPAIR INDUCTION PRESENT IN THE VARIOUS TISSUES.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

Consiglio Nazionale delle Ricerche (CNR)
EU contribution
No data
Address
Città Universitaria Piazzale Aldo Moro 5
00185 Roma
Italy

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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