CYTOGENETIC RESEARCH TO INVESTIGATE SOMATIC AND GERMINAL DAMAGE

Informazioni relative al progetto

ID dell’accordo di sovvenzione: EV3V0566

Progetto chiuso

Data di avvio 1 Giugno 1982

Data di completamento 31 Maggio 1986

Finanziato da

• Sectoral research and development programme (EEC) in the field of environment (environmental protection and climatology) - indirect and concerted actions - Environmental protection -, 1981-1985

Costo totale € 0,00

Contributo UE Nessun dato

Coordinato da

Consiglio Nazionale delle Ricerche (CNR)
Italy

Obiettivo

ELABORATION AND COMPARATIVE EVALUATION OF TEST SYSTEMS FOR THE ASSESSMENT OF GENETIC EFFECTS OF ENVIRONMENTAL CHEMICALS AND OF THE PRODUCTS OF THEIR METABOLIC TRANSFORMATION.

THE AIM OF THIS PROJECT IS TO STUDY THE CYTOGENETIC DAMAGE (SISTER-CHROMATID EXCHANGES AND CHROMOSOMAL ABERRATIONS) INDUCED BY VARIOUS CONCENTRATIONS OF DIRECT AND INDIRECT-ACTING CHEMICAL MUTAGENS ON PROLIFERATING TISSUES (BONE-MARROW, SPLEEN AND SPERMATOGONIA) AND LYMPHOCYTES STIMULATED IN VITRO OF MICE TREATED IN VIVO. PARTICULAR ATTENTION WILL BE GIVEN TO THE DIFFERENT SENSITIVITY OF GERMINAL TISSUES IN RESPECT TO SOMATIC ONES TRYING TO CORRELATE THIS DIFFERENCE TO THE METABOLISM OF THE MUTAGENS AND THE REPAIR INDUCTION PRESENT IN THE VARIOUS TISSUES.

Programma(i)

• PRE-ENVPROT 3C - Sectoral research and development programme (EEC) in the field of environment (environmental protection and climatology) - indirect and concerted actions - Environmental protection -, 1981-1985

Argomento(i)

Data not available

Invito a presentare proposte

Data not available

Meccanismo di finanziamento

CSC - Cost-sharing contracts

Coordinatore

Consiglio Nazionale delle Ricerche (CNR)

• Contributo UE: Nessun dato
• Indirizzo: Città Universitaria Piazzale Aldo Moro 5 ; 00185 Roma ; Italia
• Costo totale: Nessun dato