CYTOGENETIC RESEARCH TO INVESTIGATE SOMATIC AND GERMINAL DAMAGE

Informations projet

N° de convention de subvention: EV3V0566

Projet clôturé

Date de début 1 Juin 1982

Date de fin 31 Mai 1986

Financé au titre de

• Sectoral research and development programme (EEC) in the field of environment (environmental protection and climatology) - indirect and concerted actions - Environmental protection -, 1981-1985

Coût total € 0,00

Contribution de l’UE Aucune donnée

Coordonné par

Consiglio Nazionale delle Ricerche (CNR)
Italy

Objectif

ELABORATION AND COMPARATIVE EVALUATION OF TEST SYSTEMS FOR THE ASSESSMENT OF GENETIC EFFECTS OF ENVIRONMENTAL CHEMICALS AND OF THE PRODUCTS OF THEIR METABOLIC TRANSFORMATION.

THE AIM OF THIS PROJECT IS TO STUDY THE CYTOGENETIC DAMAGE (SISTER-CHROMATID EXCHANGES AND CHROMOSOMAL ABERRATIONS) INDUCED BY VARIOUS CONCENTRATIONS OF DIRECT AND INDIRECT-ACTING CHEMICAL MUTAGENS ON PROLIFERATING TISSUES (BONE-MARROW, SPLEEN AND SPERMATOGONIA) AND LYMPHOCYTES STIMULATED IN VITRO OF MICE TREATED IN VIVO. PARTICULAR ATTENTION WILL BE GIVEN TO THE DIFFERENT SENSITIVITY OF GERMINAL TISSUES IN RESPECT TO SOMATIC ONES TRYING TO CORRELATE THIS DIFFERENCE TO THE METABOLISM OF THE MUTAGENS AND THE REPAIR INDUCTION PRESENT IN THE VARIOUS TISSUES.

Programme(s)

• PRE-ENVPROT 3C - Sectoral research and development programme (EEC) in the field of environment (environmental protection and climatology) - indirect and concerted actions - Environmental protection -, 1981-1985

Thème(s)

Data not available

Appel à propositions

Data not available

Régime de financement

CSC - Cost-sharing contracts

Coordinateur

Consiglio Nazionale delle Ricerche (CNR)

• Contribution de l’UE: Aucune donnée
• Adresse: Città Universitaria Piazzale Aldo Moro 5 ; 00185 Roma ; Italie
• Coût total: Aucune donnée