Objective
Development of a new strategy for the assessment of adverse effects of pollution on marine organisms using the biomarker approach, and to evaluate the usefulness of biomarkers in the prediction of ecological risk.
Biochemical, physiological and behavioral biomarkers of pollutant exposure and effect will be identified in marine invertebrates. Two key questions will be addressed :
1. Can biomarkers (together with tissue pollutant residue concentrations) measured in laboratory test systems be used to predict responses in situ ?
2. Can the expression of biomarkers responses in situ be used to estimate the extent to which populations and communities are impacted by chemicals in marine ecosystems ?
Laboratory studies will focus on the development of biomarker assays. A range of invertebrate species will be utilised with most emphasis being placed on Carcinus spp. (mobile crustaceans), Mytilus spp. (sedentary, suspension-feeding molluscs) and Nereis spp. (suspension feeders-omnivorous polychaetes). These organisms will be exposed to metals (Cu, As, Hg and organotin) and to polycyclic aromatic hydrocarbons (PAHs) and polychlorinated biphenyls (PCBs). Biomarkers to be measured will include (in response to metals) free SH groups, metallothioneins, glutathione-S-transferases and stress proteins; (in response to PAHs and PCBs) monooxygenase activity, cytochrome P-450s, glutathione-S-transferases, porphyrins, fingerprints. Physiological biomarkers will include heart rate, ventilation and oxygen consumption, scope of growth, as well as a range of haemolymph parameters. Behavioral studies will focus on altered activity levels (speed and distance travelled, turning frequency, etc.). Following validation of techniques in the laboratory, biomarkers will be measured in invertebrates distributed along pollution gradients in the Baltic region, the North Sea and in the Mediterranean Sea. Transplant experiments will also be conducted in which animals are exchanged among clean and polluted sites. Biomarker responses will be related to ecologically-relevant changes in populations and communities.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences organic chemistry hydrocarbons
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences earth and related environmental sciences environmental sciences pollution
- natural sciences biological sciences ecology ecosystems
- natural sciences biological sciences zoology invertebrate zoology
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Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
RG6 6AJ READING / SILCHESTER
United Kingdom
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