Objective We shall expose two sentinel fish species to a variety of toxic environmental pollutants, and by genomic and proteomic gene expression profiling, determine adaptive responses and adverse health effects, thereby enabling selection of diagnostic biomarker gene products. Two tools will be developed for assessing the health status of coastal and estuarine environments, benefiting dependent communities and permit sustainable industrial development with maximum natural resource protection:(1) fully flexible DNA mini arrays for practically diagnosing adverse health effects and specific chemical toxicants in environments where the identities of the toxic contaminants is unknown and continually changing and,(2) quantitative analytical methods for specific gene products, for temporal trend determination. Their utility will be validated by analysis of fish from a number of polluted environments and inter-comparison with currently available methods. Fields of science natural sciencesbiological sciencesgeneticsDNAnatural sciencesbiological scienceszoologyichthyology Programme(s) FP5-EESD - Programme for research, technological development and demonstration on "Energy, environment and sustainable development, 1998-2002" Topic(s) 1.1.4.-3. - Key action Sustainable Marine Ecosystems Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator ISRAEL OCEANOGRAPHIC & LIMNOLOGICAL RESEARCH INSTITUTE Address Tel shikmona 31080 Haifa Israel See on map EU contribution € 0,00 Participants (3) Sort alphabetically Sort by EU Contribution Expand all Collapse all UNIVERSITY OF BIRMINGHAM United Kingdom EU contribution € 0,00 Address Edgbaston B15 2TT Birmingham See on map UNIVERSITY OF SOUTHERN DENMARK - UNIVERSITY OF ODENSE Denmark EU contribution € 0,00 Address 10,forskerparken 10 5230 Odense See on map UNIVERSITY OF STIRLING. United Kingdom EU contribution € 0,00 Address Stirling See on map Links Website Opens in new window