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Quantification of lung cancer risk after low radon exposure and low exposure rate: synthesis from epidemiologic and experimental data

Objectif

Occupational exposure to radon in European uranium mines during the last 30 years was at low annual rate; follow-up of 10 000 miners over more than 20 years made it possible to organise a joint analysis. This joint study has a good statistical power, able to detect lom lung cancer risks linked to low annual exposure; modifying factors like attained age, dose-rate, and concomitant exposures (gamma, ore dust) will be studied in this large cohort. Nested case-control studies will be implemented in order to test the radon-tobacco interaction. Domestic radon plus occupational exposure will be studied in one of the case-control studies. Animal experiments will be continued. Mechanistic modelling will be applied to both animal and human data.

Appel à propositions

Data not available

Régime de financement

CSC - Cost-sharing contracts

Coordinateur

INSTITUT DE RADIOPROTECTION ET DE SURETE NUCLEAIRE
Contribution de l’UE
Aucune donnée
Adresse
Rue Auguste Lemaire
92262 FONTENAY AUX ROSES
France

Voir sur la carte

Coût total
Aucune donnée

Participants (7)