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Contenido archivado el 2024-04-30

Development and application of solid-state nmr methods for the investigation of molecular structure

Objetivo



Solid-state NMR is a powerful method for investigating molecular conformation and geometry in large molecular systems. My Ph.D. work in the group of Malcolm Levitt will focus on the development of NMR techniques for the investigation of molecular structure. The use of magic-angle spinning together with dipolar recoupling schemes reactivates the magnetic couplings between neighbouring nuclear spins. In contrast to liquid-state NMR the full tensorial nature of spin-spin interactions is manifested in solid-state NMR. The optimization of the dipolar recoupling schemes for measuring bond angles instead of distances will be one part of my Ph.D. project. The other part will be the application of the developed techniques to the membrane protein rhodopsin, in order to investigate its conformation. This would involve participating in an ongoing collaboration between Malcolm Levitt's group and groups in Leiden and Oxford.

Ámbito científico (EuroSciVoc)

Programa(s)

Tema(s)

Convocatoria de propuestas

Datos no disponibles

Régimen de financiación

RGI - Research grants (individual fellowships)

Coordinador

STOCKHOLM UNIVERSITET
Aportación de la UE
Sin datos
Dirección

106 91 Stockholm
Suecia
Coste total
Sin datos

Participantes (1)