Objetivo
Research objectives and content The aim of my project is to understand the role of the tap gene in the control of neuronal connectivity in Drosophila. tap encodes a transcriptional factor with a bHLH motif which is expressed at a late stage in one of the neurons that innervate each gustatory organ. As these organs are functionally different, I believe that tap is responsible for the neuronal properties of the neuron in which it is expressed. To determine the developmental function of tap, I plan to identify loss- and gain-of-function tapmutants, and to analyse their phenotypes. This will be done by using genetic (Gal4-UAS system, FRT-FLP system, transgenic lines) as well as molecular techniques (DNA constructs) combined with DiI labelling of neurons and behavioural tests. I think that a better understanding of how tap acts will help us to understand how neuronal specificity is genetically controlled. Training content (objective, benefit and expected impact) My objective is to reach a PhD level for which I have voluntarily stopped my career as a scientific journalist. I have especially chosen the team of Dr. Alain Ghysen in Montpellier, for its particularly interesting scientific l and teaching qualities, which I think will greatly improve my capabilities in dealing with difficult scientific questions. Links with industry / industrial relevance (22)
Ámbito científico
CORDIS clasifica los proyectos con EuroSciVoc, una taxonomía plurilingüe de ámbitos científicos, mediante un proceso semiautomático basado en técnicas de procesamiento del lenguaje natural.
CORDIS clasifica los proyectos con EuroSciVoc, una taxonomía plurilingüe de ámbitos científicos, mediante un proceso semiautomático basado en técnicas de procesamiento del lenguaje natural.
Convocatoria de propuestas
Data not availableRégimen de financiación
RGI - Research grants (individual fellowships)Coordinador
34095 Montpellier
Francia