Objective
* To identify protective antigens in lymphatic Filariasis suitable for vaccine use.
* To measure human antibody and T cell responses to these antigens.
* To clone and express major T cell immunogens as recombinants.
* To express selected recombinant filarial antigens for vaccine tests in animals.
* To enhance expertise and research resources of endemic count scientists.
Expected Outcome
* Identification of a panel of immune individuals whose serological and lymphocyte reactivities will define key in immunity.
* Identification of the major T cell antigens in lymphatic Filariasis, and their cloning and expression in a variety of vectors.
* Evaluation of potential vaccine antigens against lymphatic Filariasis in rodent model systems.
* Identification of subjects exposed to Filariasis transmission but show evident immunity.
* Measurement of antibody responses to a range of recombinant antigens.
* Identification and cloning of filarial antigens which most strongly stimulate T cells.
* Analysis of different geographic strains of Brugia malayi.
* Expression of filarial T cell for vaccine testing in rodent models.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
EH9 3JT Edinburgh
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.