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CORDIS

Genetic profile of breast cancers in mediterranean countries: implications in preventive and predictive medicine

Objectif

The BreastMed consortium will compare genetics of breast tumours at the clinical and molecular levels between 2 european and 3 mediterranean countries,considering different risk factors and clinical presentation heterogeneities. Germline BRCA1 and BRCA2 mutations will be sought, and molecular profiles of gene expression of a limited number of selected genes will be analysed in breast tumours by low-density cDNA chips. In 3 years, 750 tumours or patients (and their family if hereditary predisposition is suspected), will be recruited for the study. Better genetic counselling to breast cancer risk families, medical cares adaptated to the diagnosis of hereditary breast cancer risk or expression profiles of sporadic breast tumours, and standards for DNA chips manufacturing and comparisons are the main expected results of the consortium.

Thème(s)

Data not available

Appel à propositions

Data not available

Régime de financement

CSC - Cost-sharing contracts

Coordinateur

CENTRE JEAN PERRIN
Contribution de l’UE
Aucune donnée
Adresse
Rue Montalembert 58
63011 CLERMONT-FERRAND
France

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Coût total
Aucune donnée

Participants (6)