Objetivo
Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a progressive, genetically determined cardiac disease that is a major cause of unexpected sudden death in the young and athlete in Europe. Because of its rarity, there is a need to collect data on a large scale, to set up a clinical and pathological registry to evaluate different treatments and to create a bank of DNA from affected families. The proposed research is a multidisciplinary multicenter collaborative study to investigate clinico-pathologic and genetic aspects of ARVC/D with these aims:
a) prospective longitudinal follow-up study to identify patients at risk of cardiac arrest;
b) evaluation of different therapies efficacy;
c) ultra structural and molecular pathology study to understand the etiopathogenesis;
d) genetic studies with the ultimate goal to identify the specific defective genes and the influence of the genotype on the clinical course.
Ámbito científico
Convocatoria de propuestas
Data not availableRégimen de financiación
CSC - Cost-sharing contractsCoordinador
35121 Padova
Italia