Obiettivo
Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a progressive, genetically determined cardiac disease that is a major cause of unexpected sudden death in the young and athlete in Europe. Because of its rarity, there is a need to collect data on a large scale, to set up a clinical and pathological registry to evaluate different treatments and to create a bank of DNA from affected families. The proposed research is a multidisciplinary multicenter collaborative study to investigate clinico-pathologic and genetic aspects of ARVC/D with these aims:
a) prospective longitudinal follow-up study to identify patients at risk of cardiac arrest;
b) evaluation of different therapies efficacy;
c) ultra structural and molecular pathology study to understand the etiopathogenesis;
d) genetic studies with the ultimate goal to identify the specific defective genes and the influence of the genotype on the clinical course.
Campo scientifico
Argomento(i)
Invito a presentare proposte
Data not availableMeccanismo di finanziamento
CSC - Cost-sharing contractsCoordinatore
35121 Padova
Italia