Objective Emphysema is a lung disease, characterised by abnormal enlargement of air spaces accompanied by destruction of alveoli walls and a decrease in lung densities. Investigators already discovered that Computer Tomography (CT) is informative to describe the presence and severity of emphysema in an objective manner. At our institute, software has been developed for the quantification of emphysema from CT-images. Before CT-parameters can be used in clinical research studies, it must be demonstrated to the registration authorities and pharmaceutical industry, that CT-measurements can be obtained reproducibly and that the results are more sensitive to emphysema than lung function tests. To achieve this, the software will be installed and used at 5 European hospitals to assess emphysema and to predict the effect of lung surgery on severe cases. After the expected outcome, the industry is able to start clinical trials to evaluate possible treatment of emphysema. Fields of science natural sciencescomputer and information sciencessoftwaremedical and health sciencesclinical medicinesurgery Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases Call for proposal Data not available Funding Scheme DEM - Demonstration contracts Coordinator LEIDEN UNIVERSITY EU contribution No data Address 22,Albinusdreef 22 P4-25 2300 RC LEIDEN Netherlands See on map Total cost No data Participants (4) Sort alphabetically Sort by EU Contribution Expand all Collapse all LUND UNIVERSITY Sweden EU contribution No data Address Paradisgatan 2 221 00 LUND See on map Total cost No data UNIVERSITY HOSPITAL OF ZUERICH Switzerland EU contribution No data Address Raemistrasse 100 8091 ZURICH See on map Total cost No data UNIVERSITY OF BIRMINGHAM United Kingdom EU contribution No data Address EDGBASTON B15 2TT BIRMINGHAM See on map Links Website Opens in new window Total cost No data UNIVERSITY OF COPENHAGEN Denmark EU contribution No data Address 10 2900 HELLERUP See on map Total cost No data