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Demonstration of the performance of a new analytical software package developed for detection of progress of emphysema by computer tomography

Objectif

Emphysema is a lung disease, characterised by abnormal enlargement of air spaces accompanied by destruction of alveoli walls and a decrease in lung densities. Investigators already discovered that Computer Tomography (CT) is informative to describe the presence and severity of emphysema in an objective manner. At our institute, software has been developed for the quantification of emphysema from CT-images. Before CT-parameters can be used in clinical research studies, it must be demonstrated to the registration authorities and pharmaceutical industry, that CT-measurements can be obtained reproducibly and that the results are more sensitive to emphysema than lung function tests. To achieve this, the software will be installed and used at 5 European hospitals to assess emphysema and to predict the effect of lung surgery on severe cases. After the expected outcome, the industry is able to start clinical trials to evaluate possible treatment of emphysema.

Appel à propositions

Data not available

Régime de financement

DEM - Demonstration contracts

Coordinateur

LEIDEN UNIVERSITY
Contribution de l’UE
Aucune donnée
Adresse
22,Albinusdreef 22 P4-25
2300 RC LEIDEN
Pays-Bas

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Coût total
Aucune donnée

Participants (4)