Objetivo
Emphysema is a lung disease, characterised by abnormal enlargement of air spaces accompanied by destruction of alveoli walls and a decrease in lung densities. Investigators already discovered that Computer Tomography (CT) is informative to describe the presence and severity of emphysema in an objective manner. At our institute, software has been developed for the quantification of emphysema from CT-images. Before CT-parameters can be used in clinical research studies, it must be demonstrated to the registration authorities and pharmaceutical industry, that CT-measurements can be obtained reproducibly and that the results are more sensitive to emphysema than lung function tests. To achieve this, the software will be installed and used at 5 European hospitals to assess emphysema and to predict the effect of lung surgery on severe cases. After the expected outcome, the industry is able to start clinical trials to evaluate possible treatment of emphysema.
Ámbito científico
Convocatoria de propuestas
Data not availableRégimen de financiación
DEM - Demonstration contractsCoordinador
2300 RC LEIDEN
Países Bajos