The role of tissue transglutaminase in inducing gluten t cell response and autoantibody formation in coeliac disease

Project Information

FLECKENSTEIN, BURKHA

Grant agreement ID: QLG1-CT-2000-51218

Project closed

Start date 1 January 2001

End date 31 December 2001

Funded under

• Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Total cost € 71 574,00

EU contribution € 71 574,00

Coordinated by

THE NATIONAL HOSPITAL UNIVERSITY OF OSLO
Norway

Objective

Deamidation and transamidation activities of tTG are measured and the influence of tTG autoantibodies is determined. Gluten-tTG complexes are applied to investigate the role of cognate T/B cell interaction for the formation of tTG autoantibodies. An in vitro marine system, a marine adoptive transfer model and an in vitro human system will be used.

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

THE NATIONAL HOSPITAL UNIVERSITY OF OSLO

• EU contribution: No data
• Address: Pilestredet 32 ; 0027 OSLO ; Norway
• Total cost: No data