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The role of tissue transglutaminase in inducing gluten t cell response and autoantibody formation in coeliac disease

Objectif

Deamidation and transamidation activities of tTG are measured and the influence of tTG autoantibodies is determined. Gluten-tTG complexes are applied to investigate the role of cognate T/B cell interaction for the formation of tTG autoantibodies. An in vitro marine system, a marine adoptive transfer model and an in vitro human system will be used.

Appel à propositions

Data not available

Coordinateur

THE NATIONAL HOSPITAL UNIVERSITY OF OSLO
Contribution de l’UE
Aucune donnée
Adresse
Pilestredet 32
0027 OSLO
Norvège

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Coût total
Aucune donnée