Objectif
The leukotrienes (LT) are important lipid signalling molecules in chronic inflammatory disorders affecting, e.g. the joints and respiratory system, which are serious health problems with a major socio-economic impact. Our network, positioned in the international forefront of LT research, will carry out a multidisciplinary project with the aims to elucidate the underlying LT-dependent disease mechanisms and contribute to the development of novel therapeutic strategies and anti-LT drugs. The work will focus on molecular studies of key enzymes and receptors, regulation of cellular LT synthesis, the role of LTs in the immune system and characterisation of new potential drug targets, in combination with applied studies in complex models of inflammatory diseases. Our project will be conducted in alliance with the industry and has the potential for future extension into medical practice and treatment of chronic and degenerative diseases.
Champ scientifique
CORDIS classe les projets avec EuroSciVoc, une taxonomie multilingue des domaines scientifiques, grâce à un processus semi-automatique basé sur des techniques TLN.
CORDIS classe les projets avec EuroSciVoc, une taxonomie multilingue des domaines scientifiques, grâce à un processus semi-automatique basé sur des techniques TLN.
- medical and health sciencesclinical medicinepneumology
- medical and health scienceshealth sciencesinflammatory diseases
- medical and health sciencesbasic medicineimmunology
- natural sciencesbiological sciencesbiochemistrybiomoleculeslipids
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsenzymes
Appel à propositions
Data not availableRégime de financement
CSC - Cost-sharing contractsCoordinateur
171 77 STOCKHOLM
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