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Content archived on 2024-05-15

Improved healthcare for patients with primary antibody deficiencies through new strategies elucidating their pathophysiology (IMPAD)

Objective

Primary antibody deficiencies like common variable immunodeficiency, IgA-deficiency and the non-X-linked hyper-IgM syndrome are rare, chronic diseases that are severely complicated by recurrent bacterial infections, poorly recognized in daily medical practice and expensive to treat. To understand their unknown etiologies, our multidisciplinary approach combines 10 European groups to identify the genetic origins of the deficiencies, the genetic risk factors in different European populations, the defects and changes in inter- and intracellular signalling pathways and their pathophysiological relations to immunological phenotypes and function.

Call for proposal

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Coordinator

UNIVERSITAETSKLINIKUM FREIBURG
EU contribution
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Address
Hugstetter Strasse 55
79106 FREIBURG (IN BREISGAU)
Germany

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Total cost
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Participants (8)