Objetivo To unravel the molecular mechanisms underlying proper mammalian development is one of the most pressing tasks for modern biomedical science. The complicated processes leading to genetic disease can only be understood, if we comprehend normal development. To study differentiation processes we have decided to focus on the development of the go- and, which is widely believed to be the best model system. We are planning to elucidate differentiation on a molecular level using a variety of approaches. In vitro studies will be performed to define interactions between known factors. Transgenic and knock-out animals will be generated to analyse gene function in an in vivo environment. Positional cloning of genes from patients with sex-reversal phenotypes will be used to identify new players in the explore patterns of evaluation in this highly diverged system. Programa(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Tema(s) 1.1.1.-8. - Research into genomes and diseases of genetic origin Convocatoria de propuestas Data not available Régimen de financiación CSC - Cost-sharing contracts Coordinador UNIVERSITY OF NEWCASTLE UPON TYNE Aportación de la UE Sin datos Dirección Central Parkway NE1 3BZ NEWCASTLE UPON TYNE Reino Unido Ver en el mapa Coste total Sin datos Participantes (3) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE Francia Aportación de la UE Sin datos Dirección Rue de la Cardonille 141 34396 MONTPELLIER Ver en el mapa Coste total Sin datos MEDICAL RESEARCH COUNCIL Reino Unido Aportación de la UE Sin datos Dirección Crewe Road Western General Hospital EH4 2XU EDINBURGH Ver en el mapa Coste total Sin datos UNIVERSITA DEGLI STUDI DI PAVIA Italia Aportación de la UE Sin datos Dirección Via Forlanini 14 27100 PAVIA Ver en el mapa Coste total Sin datos