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Content archived on 2024-05-15

Control of specification and migration of oligodendrocytes

Objective

The study of cellular and molecular mechanisms underlying oligodendrocytedevelopment is a prerequisite to understand pathologies linked to myelin dysfunction. During development, the oligodendroglial specification of intraepithelial cells is a process spatially restricted which gives rise to a diversity of oligodendrocyte cells types. The aim of our project is to study, from multidisciplinary approaches (molecular and cellular) and in different animal models (Drosophilae, chick, mouse):
i) the developmental mechanisms regulating the oligodendrogenesis from undifferentiated intraepithelial precursors: focusing on genetic cascade that controls the choice of oligodendroglial lineage; and
ii) the biological consequences of molecular and spatial differentiate characters of oligodendrocyte progenitors; focusing the migration patterns and their molecular control.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE
EU contribution
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Address
Campus de San Juan - Ctra Alicante-Valencia Km 8,7
03550 SAN JUAN DE ALICANTE
Spain

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (6)

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